马铃薯Y病毒属病毒P3和P3-PiPo蛋白功能研究进展  

The functional characterization of Potyvirus-encoded P3 and P3-PiPo protein

作　　者：崔晓艳[1] 陈新[1] 顾和平[1] 张红梅[1] 陈华涛[1] 袁星星[1] 

机构地区：[1]江苏省农业科学院蔬菜研究所,江苏南京210014

出　　处：《微生物学通报》2012年第1期99-105,共7页Microbiology China

基　　金：国家自然科学基金项目(No.31101411);江苏省农业科技自主创新基金项目[No.CX(11)4044]

摘　　要：Potyvirus属于马铃薯Y病毒科Potyviridae,是最大的植物病毒属,给农业生产造成严重的经济损失。P3是Potyvirus属病毒中变异很大、功能较复杂的编码蛋白,涉及到病毒复制、侵染、抗性及细胞间运动;P3-PiPo是P3编码框内新近发现的Potyvirus重要编码蛋白,已证实它在病毒的细胞间运动中起着决定性的作用。对病毒蛋白功能的研究为该属病毒的研究发展提供重要的理论基础,对Potyvirus侵染机制及抗病机理研究具有指导价值。Potyvirus belonging to family Potyviridae, is the largest plant virus family, which can be responsible for severe economic losses to agriculture world-wide. P3 protein of potyviruses show relatively low homology in compared to other proteins among potyviruses and multi-functional, related with virus replication, infection, resistance and cell-to-cell movement. P3-PiPo, the newly found SMV-encoded protein, is an overlap protein produced via ribosomal frameshifting or transcriptional slippage at a highly conserved within the P3 cistron and play a key role in viral cell-to-cell movement. The functional characterization of potyvirus-encoded proteins supported the understanding of potyviruses, and promoted the research of potyviruses infectious and resistant mechanisms.

关 键 词：马铃薯Y病毒属(Potyvirus) P3蛋白 P3-PiPo蛋白 

分 类 号：S432.41[农业科学—植物病理学]