番泻叶提取物的吸湿性及辅料对其影响的研究  

Study on the Moisture Absorption Properties of Sennae Folium Extract and Effects of Optimizing Excipients

作　　者：彭淑娟[1] 王亚静[1] 田慧[1] 孙士真[1] 王艳明[1] 

机构地区：[1]天津中医药大学天津市现代中药重点实验室/省部共建国家重点实验室培育基地,天津300193

出　　处：《中国药房》2012年第3期225-227,共3页China Pharmacy

摘　　要：目的:研究番泻叶提取物的吸湿性,探讨辅料对番泻叶提取物吸湿性的影响。方法:采用粉末吸湿法,测定样品的吸湿率;以平均吸湿速度、吸湿加速度、吸湿初速度、临界相对湿度等吸湿参数为指标,考察番泻叶提取物的吸湿性及辅料对其的影响。结果:辅料均不同程度地降低了番泻叶提取物的平均吸湿速度,其中乳糖的作用最强;但乳糖对番泻叶提取物的临界相对湿度几乎没有影响。结论:辅料的合理使用可以改善番泻叶提取物的吸湿性。OBJECTIVE： To study the moisture absorption properties of Sermae Folium extract, and to investigate the influenc- es of optimizing excipients on it. METHODS：The moisture absorption percent of samples were determined with powder moisture absorption method, and the moisture absorption properties of Sennae Folium extract and the effects of optimizing excipients were in- vestigated using average moisture absorption speed, moisture absorption accelerated speed, initial speed and the critical relative hu- midity as index. RESULTS：The average moisture absorption speed was decreased by excipients in different degree and the lactose is one of the most efficient; However, it had little effect on the critical relative humidity of Sennae Folium extract. CONCLUSION： Rational use of excipients can improve the moisture absorption of Sennae Folium extract.

关 键 词：番泻叶提取物 辅料 吸湿速度 临界相对湿度 

分 类 号：R283.1[医药卫生—中药学] R284.2[医药卫生—中医学]