芍红消积颗粒的质量标准研究  

Study on Quality Standard of Shaohong Xiaoji Granules

作　　者：弓晓东[1] 谈瑄忠[2] 毛春芹[1] 陆兔林[1] 苏丹[1] 

机构地区：[1]南京中医药大学药学院,南京210046 [2]南京市中医院,南京210001

出　　处：《中国药房》2012年第3期250-252,共3页China Pharmacy

基　　金：南京市科技发展计划项目(200901086)

摘　　要：目的:建立芍红消积颗粒的质量标准。方法:采用薄层色谱(TLC)法对方中的赤芍、三棱、黄芪、黄芩进行定性鉴别,用高效液相色谱法对方中芍药苷进行含量测定。结果:TLC斑点清晰、分离度好,阴性对照无干扰;芍药苷检测浓度在0.0521～0.5210mg.mL-1范围内与峰面积积分值呈良好的线性关系(r=0.9998),平均回收率为97.49%,RSD=1.80%(n=9)。结论:所建标准可用于芍红消积颗粒的质量控制。OBJECTIVE： To establish the quality standard of Shaohong xiaoji granules. METHODS： TLC was used for the qualitative identification of Paeoniae Radix Rubra, Sparganium stoloniferum, Astragali Radix and Scutellaria baicalensis. HPLC was used to determine the content of paeoniflorin. RESULTS： TLC spots were clear and well-separated without negative interference. The linear range of paeoniflorin was 0.052 1-0.521 0 mg. mL^-1 （r=0.999 8） with an average recovery of 97.49% （RSD= 1.80%, n = 9）. CONCLUSION：Established standard is suitable for the quality control of Shaohong xiaoji granules.

关 键 词：芍红消积颗粒 质量标准 芍药苷 薄层色谱法 高效液相色谱法 

分 类 号：R284.2[医药卫生—中药学] R283.627[医药卫生—中医学]