蛛网膜下腔联合硬膜外腔阻滞分娩镇痛对脐血血气及妊娠结局的影响  

Influence on Maternal and Umbilical Cord Blood Gas in Spinal-epidural Analgesia and Patient-control Epidural Analgesia

作　　者：滕奔琦[1] 侯红瑛[1] 李萍[1] 朱娟[1] 范建辉[1] 

机构地区：[1]中山大学附属第三医院妇产科,广东广州510630

出　　处：《中山大学学报（医学科学版）》2011年第6期799-802,共4页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：广东省自然科学基金(10151008901000127)

摘　　要：【目的】探讨蛛网膜下腔阻滞加硬膜外阻滞分娩镇痛对母儿及脐血血气的影响。【方法】选取在我院住院分娩的自愿接受分娩镇痛的产妇50例作为观察组,选取同期入院未加任何镇痛干预的自然分娩初产妇34例作为对照组,观察两组产程及母儿结局,同时对两组新生儿脐动脉进行血气分析,比较其pH值、氧分压(PaO2)、二氧化碳分压(PaCO2)。【结果】镇痛组潜伏期、活跃期及第二产程时间较对照组延长,但是其母儿并发症无增加;脐动脉血pH值、PaO2、PaCO2为7.27±0.06、(58.40±9.12)mmHg、(17.07±6.41)mmHg,对照组为7.29±0.06、(55.11±8.64)mmHg、(16.89±5.08)mmHg,两组比较差异无统计学意义。【结论】CSEA+PCEA分娩镇痛对脐血血气和妊娠结局无不良影响。[Objective] To study whether combined spinal-epidural analgesia （CSEA） and patient-control epidural analgesia （PCEA） has influence on maternal and umbilical cord blood gas. [ Methods ] Fifty healthy nulliparas who accepted CSEA＋PCEA were selected as the study group, meanwhile another 34 nulliparas without CSEA＋PCEA were selected as the control group, they all had vaginal delivery. The delivery process and the effect on mother and fetus were compared between the two groups. The blood gas analysis of the newborn umbilical arterial blood was observed （pH, PO2, and PCO2）. [Result] Though the duration of latent phase, active phase and the second stage of labor in the analgesia group were longer than the control group, the complications of mother and fetus were not increased. The pH, PO2, and PCO2 of umbilical arterial blood in the analgesia group and the control group were （7.27 ＋ 0.06） vs （7.29 _＋ 0.06）, （58.40 ＋_ 9.12） mmHg vs （55.11 _＋ 8.64） mmHg, （17.07 _＋ 6.41） mmHg vs （16.89 _＋ 5.08） mmHg. There were no significant differences in two groups （P 〈 0.05 ）. [ Conclusions ] CSEA ＋PCEA have no impact on umbilical cord blood gas and pregnancy outcome.

关 键 词：腰麻-硬膜外联合麻醉 分娩镇痛 血气分析 妊娠结局 

分 类 号：R714.3[医药卫生—妇产科学]