血浆CRP、FPA、F1+2检测在溃疡性结肠炎中的临床分析  

Clinical Value of Blood Plasma FPA,F1+2 and CRP Detection in Ulcerative Colitis Diagnosis

作　　者：王兴木[1] 

机构地区：[1]浙江省绍兴市人民医院检验科,312000

出　　处：《医学研究杂志》2011年第12期130-132,共3页Journal of Medical Research

摘　　要：目的探讨在溃疡性结肠炎(UC)患者中检测血浆FPA、F1+2和CRP浓度的临床价值。方法分别检测30例正常对照组、40例活动期溃疡性结肠炎和40例缓解期溃疡性结肠炎的血浆FPA、F1+2和CRP水平,活动期溃疡性结肠炎按病情轻重分组统计其血浆FPA、F1+2和CRP的水平。结果活动期患者血浆FPA、F1+2和CRP水平高于缓解期患者和对照组,缓解期患者也高于对照组,差异有显著性(P<0.01);活动期患者按疾病不同严重度进行分组统计,结果显示血浆FPA,F1+2和CRP水平随着疾病严重程度升高,差异显著(P<0.05)。结论 UC患者血浆CRP、FPA和F1+2明显升高且其血浆水平的变化与UC患者活动性、疾病严重度有关,对UC患者检测血浆CRP、FPA和F1+2水平,可能对疾病活动度和严重度及疗效评价有一定的价值。Objective To explore the clinical value of blood plasma FPA,F1 ＋ 2 and CRP in the patients with ulcerative colitis （ UC）. Methods The blood plasma FPA,F1 ＋ 2 and CRP level were detected in 40 cases of ulcerative colitis on active stage and 40 ca- ses on paracme, and 30 healthy controls. Results The blood plasma FPA,F1 ＋ 2 and CRP level in active stage group and in paracme group were higher than those in control group significantly（P 〈0. 05）. It also had difference between active stage group and paracme group（ P 〈 0.05）. The active stage group was divided according to its severity degree, and it showed that the FPA, F1 ＋ 2 and CRP level were increased with the development of the disease（P 〈 0.05）. Conclusion The FPA,F1 ＋ 2 and CRP level were increased in patients with UC, and they changed with the reactiveness and severity degree of UC. The FPA, F1 ＋ 2 and CRP level could be involved in the as- sessment of the severity degree and therapeutic effect in UC.

关 键 词：溃疡性结肠炎 纤维蛋白肽A 凝血酶原片段1+2 C反应蛋白 

分 类 号：R256.39[医药卫生—中医内科学]