影响经皮冠状动脉介入术预后的危险因素分析  

Analysis of Risk Factors Affecting Prognosis of Percutaneous Coronary Intervention

作　　者：张娅[1] 陈慧[2] 李灿东[3] 吴红霞[2] 林云钗[2] 洪丹丹[2] 王建军[2] 

机构地区：[1]福建中医药大学中西医结合研究院,福建福州350108 [2]福建医科大学省立临床医学院心内科,福建福州350001 [3]福建中医药大学中医证研究基地,福建福州350108

出　　处：《辽宁中医杂志》2012年第1期87-89,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：卫生部科学研究基金-福建省卫生教育联合攻关计划项目(WKJ2008-2-59)

摘　　要：目的:探讨影响经皮冠状动脉介入术(PCI)预后的危险因素。方法:371例行PCI成功的冠心病患者根据术后1年是否发生主要心血管事件分为发生组和未发生组,对可能影响PCI预后的危险因素进行多因素Logistic回归分析。结果:单因素分析和多因素Logistic回归分析显示气虚血瘀证、MPA(≥70%)、血浆vWF水平和CYP2C19*2基因突变是影响PCI术后1年主要心血管事件的独立危险因素。结论:气虚血瘀证、血浆vWF水平、MPA70%切割点和CYP2C19*2基因突变对评价PCI预后具有重要意义。Objective：To research the risk factors affecting the prognosis in patients undergoing PCI. Methods：371 CHD patients after receiving successful PCI were adopted in this study. They were divided into with major adverse cardiac events（MACE） group and without MACE group. Multivariate logistic analysis was used to analyze the independent influencing factors of prognosis after PCI. Results ： The univariate analysis and logistic regression analysis indicated that qi deficiency and blood stasis syndrome, more than 70% in maximum platelet aggregation rate （MPA）, the level of plasma von Willebrand factor（vWF） and CYP2C 19 ＊ 2 gene mutation were the independent risk factors of MACE in the first following year after PCI. Corvclusion ： Qi deficiency and blood stasis syndrome ,70% cut -off in MPA ,the level of plasma vWF and CYP2C19 ＊ 2 gene mutation are very important to evaluate the prognosis for CHD patients after receiving successful PCI.

关 键 词：经皮冠状动脉介入术 预后 危险因素 主要心血管事件 

分 类 号：R541.4[医药卫生—心血管疾病]