家兔髂骨中无机元素浓度和血清生化参量的测定  

Determinations of inorganic elements in iliac crests and biochemical parameters in serum of rabbits

作　　者：张元勋[1] 李德义[1] 庄圭荪[1] 张桂林[1] 王智兴[2] 夏筠[3] 

机构地区：[1]中国科学院上海原子核研究所,上海201800 [2]上海第二医科大学附属瑞金医院,上海200025 [3]上海市伤骨科研究所,上海200025

出　　处：《核技术》2000年第1期39-42,共4页Nuclear Techniques

基　　金：中国科学院科学基金!KJ951-A1-409;国家自然科学基金!19875074

摘　　要：培育家兔造成骨质疏松模型，用于研究妇女骨质疏松患者骨中无机元素的变化机理。使用中子活化分析技术测定３０例家兔髂骨中无机元素含量。结果表明，实验组中Ｆ元素含量较对照组显著增高（Ｐ＜０．００１），Ｍｇ元素含量显著减少（Ｐ＜０．００１），而其它元素如Ｋ、Ｎａ、Ｃａ、Ｂａ、Ｍｎ、Ｓｒ在两组之间无显著差异。结合家兔血清生化指标的测定，探讨了元素对维持正常骨结构的意义。This paper dealt with the osteoporosis model of New Zealand rabbits in order tostudy the functions of inorganic elements for women patients with osteoporosis.Thirty cases of iliac crest were collected and determined using Neutron ActivationAnalysis (NAA) technique. The results showed that the fluorine concentrations inthe experimental group were higher than those in the control group and themagnesium concentrations were significantly lower (P<0.001), but theconcentrations of K, Na, Ca, Ba, Mn, Sr had no remarkable difference. Combinedwith the serum biochemical markers of bone formation and resorption, thephysiological functions of some metal elements in bone were discussed.

关 键 词：骨质疏松 无机元素 中子活化分析 骨结构 

分 类 号：R817.48[医药卫生—影像医学与核医学] O657.4[医药卫生—放射医学]