女性急性冠状动脉综合征患者的临床特点分析  

Clinical characteristics and complications of acute coronary syndrome in women

作　　者：王曦之[1] 陈韵岱[2] 米树华[1] 贾淑杰[1] 周芸[1] 杨红霞[1] 关杨[1] 

机构地区：[1]首都医科大学附属北京安贞医院特需医疗科,100029 [2]解放军总医院心内科

出　　处：《中国医药》2012年第1期13-15,共3页China Medicine

摘　　要：目的 探讨女性急性冠状动脉综合征（ACS）患者的临床特点.方法 整理明确诊断为ACS的住院患者的病历资料,比较472例住院女性ACS患者与1277例男性ACS患者的临床诊治及并发症特点.结果 女性ACS的发病年龄较男性大,60岁以后发病比例女性明显比男性高[83.6％ （395/472）比70.2％（ 896/1277）]；女性患者发病到就诊的时间长[（131±35）h比（114±36）h],住院时间长[（13±3）d比（12±4）d],2组比较差异均有统计学意义（P＜0.05）.女性ACS患者危险因素较多,较男性合并糖尿病[36.7％（ 173/472）比22.1％ （283/1277）]、高血压[72.5％ （342/472）比60.9％ （778/1277）]多,2组比较差异有统计学意义（P＜0.05）.诊断不稳定型心绞痛的女性患者明显多于男性患者[50.0％（236/472）比37.4％（ 478/1277）],而诊断急性心肌梗死的女性少于男性[42.4％（200/472.比58.1％ （742/1277）],2组比较差异有统计学意义（P＜0.05）.女性选择经皮冠状动脉介入治疗术[50.2％（237/472）比63.8％ （825/1277）]及冠状动脉搭桥术[1.3％（6/472）比3.9％（49/1277）]治疗者少于男性,2组比较差异有统计学意义（P＜0.05）.结论 女性ACS患者并发症多,预后较男性差.Objective To analyze the clinical characteristics and complications of acute coronary syndrome （ACS） in women.Methods Clinical characteristics and complications of 313 women and 857 men diagnosed of ACS in GRACE Study were observed.Results Women with ACS were older than men.The women＇s morbidity was significantly higher than that of men older than sixty[ 83.6% （395/472） vs 70.2% （896/1277） ].It takes longer time from onset to see a doctor in female patient with ACS than in male patient with ACS[ （131 ± 35 ）h vs （114 ± 36） h ],and the duration of hospital stay in female patient with ACS is longer than that in male patient with ACS [ （ 13 ±3）d vs （ 12 ±4）d] （P 〈0.05）.Women with ACS had more risk factors than men.Diabetes[ 36.7% （ 173/ 472）vs 22.1%（283/1277）] and Hypertension[72.5% （342/472） vs 60.9% （778/1277）] were more important for women than for men （ P 〈 0.05 ）.The number of women diagnosed of unstable angina pectoris was more than that of men[ 50.0% （236/472） vs 37.4% （478/1277） ],while the number of women diagnosed of acute myocardial infarction was less than that of men[42.4% （200/472） vs 58.1% （742/1277） ].Less female patients had percutaneous coronary intervention （ PCI ） [ 50.2% （ 237/472 ） vs 63.8% （ 825/1277 ） ] and coronary artery bypass graft （CABG） （ P 〈 0.05 ） [ 1.3 % （6/472） vs 3.9% （49/1277 ） ].Conclusions Female patients with ACS have more complications and worse prognosis than male patients with ACS.

关 键 词：冠状动脉疾病 急性冠状动脉综合征 女性 并发症 

分 类 号：R541[医药卫生—心血管疾病]