祖师麻总香豆素的提取工艺研究  

Study on extraction of total Coumarin in Cortex Daphnes

作　　者：何军民 杨鸽华 闫志健[3] 王丽丽[3] 石森林[3] 

机构地区：[1]浙江东阳市红十字会医院,东阳322221 [2]浙江诸暨市人民医院,诸暨311800 [3]浙江中医药大学药学院,浙江310053

出　　处：《海峡药学》2011年第12期86-88,共3页Strait Pharmaceutical Journal

摘　　要：目的优选祖师麻总香豆素的提取工艺。方法建立祖师麻总香豆素的紫外分光光度测定方法,采用L9(34)正交设计,对祖师麻总香豆素的提取条件进行优化。结果方法学考察表明,精密度、稳定性、重现性、回收率等均符合要求;祖师麻总香豆素的最佳提取工艺为10倍量乙醇、回流提取1.5h、提取3次,以此条件提取祖师麻总香豆素的提取率达到25.7%。结论本研究建立的祖师麻总香豆素UV测定方法稳定、可靠、简便;确定的祖师麻总香豆素提取条件科学合理、稳定可行。OBJECTIVE To study the extraction of total coumarin in cortex daphnes.METHODS The extraction condiction was optimized with orthogonal design by the detection of UV spectrum.RESULTS Total coumarin extraction was affected by extraction frequency,solvent quantity,extraction time.CONCLUSION The study of measuring cortex daphnes by UV are stable,credible and convenient.The extraction condition are reasonable and feasible.

关 键 词：祖师麻 总香豆素 提取工艺 

分 类 号：R282.7[医药卫生—中药学]