类风湿关节炎血液学改变的研究  

Study on hematological system changes in rheumatoid arthritis

作　　者：王亮[1] 许琳[2] 卓光生[3] 

机构地区：[1]天津市第四中心医院,天津300140 [2]天津市公安医院,天津300042 [3]福建医科大学第一附属医院,福建福州350005

出　　处：《吉林医学》2012年第1期23-25,共3页Jilin Medical Journal

摘　　要：目的:分析类风湿关节炎(Rheumatoid Arthritis,RA)疾病活动时血液学改变及反应疾病活动的炎性指标的变化,并探讨这些指标间的相互关系。方法:对住院治疗的120例RA疾病活动期患者进行回顾性研究,探讨血液学改变情况。结果:贫血发病率较高,为69.2%,主要为慢性病贫血(Anemia of chronic disease,ACD);中性粒细胞及单核细胞增高也较明显,中性粒细胞减少少见,淋巴细胞稍有减少,血小板增多多见。血小板与临床常用的几种炎症指标相关性分析显示有不同程度的相关性。结论:疾病活动期的RA患者血液学改变中贫血常见,主要为ACD,与代表铁储备的血清铁蛋白成负相关关系;血小板增多可以作为反应炎性反应活动的重要指标。Objective To analyze the hematological system and inflammation index changes in rheumatoid arthritis（RA）,and explore the interrelation of these indexes.Method Total 120 cases with RA was retrospectively analyzed,and explore the hematological system changes.Results The anemia incidence was higher（69.2%）,mainly the anemia of chronic disease（ACD）,the increases of neutrophil and monocyte was obvious,neutrophil decrease was not common,lymphocyte showed slight decrease,thrombocytosis was common.The correlation analysis between platelet and several inflammation indexes showed correlation of different degree.Conclusion RA patients in active period often has anemia,mainly the ACD,is negative correlated with serum ferritin,thrombocytosis is the important index for inflammation activity.

关 键 词：类风湿关节炎 慢性病贫血 中性粒细胞增多 血小板增多 

分 类 号：R593.22[医药卫生—内科学]