基于GATE的双平板正电子发射乳腺断层成像系统的仿真研究  

Simulation studies of flat-panel PEM detectors based on GATE

作　　者：董晓霞[1] 汪梦蝶[1] 胡广书[1] 张辉[1] 

机构地区：[1]清华大学医学院,北京100084

出　　处：《核技术》2012年第1期60-64,共5页Nuclear Techniques

摘　　要：采用Monte Carlo法仿真软件GATE,构建专用于乳腺成像的双平板正电子发射断层成像系统PEM并研究其性能。参考NEMA NU 4–2008标准,并在试验中略作改动。研究了PEM(positron emission mammography)的灵敏度、散射分数、晶体散射、计数率、固有空间分辨率等参数。结果表明,在350–650 keV能窗、6 cm平板间距下,系统灵敏度达14.17%,固有空间分辨率约1.2 mm;乳腺仿体活度为29.6 MBq时,噪声等效计数率NECR为1.508×105/s,满足PEM系统所需。In this work, we used the GATE code to simulate a dual-head positron emission mammography （PEM） system using LYSO detectors and evaluate its performances. The NEMA NU 4-2008 standard, modified slightly, was referred for the PEM system. System performances of sensitivity, phantom scattering, crystal scattering, counting rate and intrinsic spatial resolution were simulated. A peak absolute sensitivity of 14.17%, intrinsic spatial resolution of 1.2 mm and the peak NEC rate of 1.508×10^5/s at an activity of 29.6 MBq in a breast phantom were found at a 350-650 keV energy window and 6 cm detector separation, meeting the system needs.

关 键 词：乳腺癌 双平板PEM MONTE CARLO模拟 GATE 

分 类 号：R445.6[医药卫生—影像医学与核医学]