甲基强的松龙联合布地奈德、复方异丙托溴铵雾化吸入对中重度AECOPD的疗效  

Efficacy of methylprednisolone combined with inhalation of budesonide and compound ipratropium bromide for moderate and severe patients with AECOPD

作　　者：何世贵[1] 朱晓兰[1] 房三友[1] 

机构地区：[1]扬州大学医学院附属泰兴医院呼吸病科,泰兴市225400

出　　处：《江苏医药》2011年第24期2936-2938,共3页Jiangsu Medical Journal

摘　　要：目的观察静脉使用甲基强的松龙联合布地奈德、复方异丙托溴铵雾化吸入治疗中、重度慢性阻塞性肺疾病急性加重期(AECOPD)患者的疗效。方法 64例筛选合格的中、重度AECOPD患者随机均分为治疗组和对照组。在常规治疗的基础上,治疗组静脉使用甲基强的松龙,并加用布地奈德、复方异丙托溴铵雾化吸入;对照组只予静脉使用甲基强的松龙。治疗1周后观察疗效。结果治疗后,两组临床症状、肺功能及血气分析均有改善,治疗组改善更明显。结论静脉应用甲基强的松龙联合布地奈德、复方异丙托溴铵对改善中、重度AECOPD患者的临床症状、肺功能等方面有较好疗效。Objective To observe the efficacy of intravenous methylprednisolone combined with inhalation of budesonide and compound ipratropium bromide for moderate and severe patients with acute exacerbation of chronic obstructive pulmonary disease（AECOPD）.Methods Sixty-four moderate and severe AECOPD patients were equally randomized into two groups.On the basis of conventional therapy,the patients in group A were given intravenous methylprednisolone combined with inhalation of budesonide and compound ipratropium bromide,those in group B were treated with intravenous methylprednisolone alone.The efficacy was evaluated one week later.Results After treatment,clinical symptoms,pulmonary function test and blood gas analysis were improved more in group A than those in group B.Conclusion Intravenous methylprednisolone combined with inhalation of budesonide and compound ipratropium bromide is effective in treating the patients with AECOPD.

关 键 词：甲基强的松龙 布地奈德 复方异丙托溴铵 慢性阻塞性肺疾病 

分 类 号：R563[医药卫生—呼吸系统]