可降解铁基心血管支架材料的研究进展  

Research Progress on Iron-based Biodegradable Coronary Stents

作　　者：徐文利[1,2] 吴竞尧[1,3] 谭丽丽[1] 杨柯[1] 

机构地区：[1]中国科学院金属研究所,沈阳110016 [2]中国科学院研究生院,北京100049 [3]中国科学技术大学化学与材料科学学院,合肥230026

出　　处：《材料导报》2012年第1期75-78,共4页Materials Reports

基　　金：国家重点基础研究发展计划(973)项目(2012CB619101)

摘　　要：概述了可降解铁基心血管支架材料的研究历史及现状,介绍了可降解铁基心血管支架的优势及其早期动物实验结果。结果表明,铁基合金是一种非常适宜制作可降解心血管支架的材料,但其存在降解速度过慢的问题。在分析可降解铁基合金的最新研究进展基础上,认为在提高铁基合金的降解速度方面虽然目前已经进行了很多有益的尝试,但是尚无极具意义的结果。同时提出,应在对人体环境下铁基合金的降解行为研究基础上发展新的提高铁基合金降解速度的方法。The history and current status of studies on iron-based coronary stents are summarized, and the ad- vantage of iron-based biodegradable stents and preliminary results of animal tests are presented. The results show that iron-based alloy is a suitable biodegradable coronary stent material, but the low degradation rate is its existing problem. On the basis of the analysis of the novel research progress investigation of biodegradable iron-based alloy, it is presented that though many useful attempts have been made to improve the degradation rate, no instructive result has been achieved. It is suggested that the biodegradation mechanism of iron-based alloy in human body be studied to develop novel methods to improve its degradation rate.

关 键 词：生物可降解 心血管支架 铁基合金 降解速度 

分 类 号：TG139.8[一般工业技术—材料科学与工程]