银线草中一个新的桉烷型倍半萜内酯(英文)  

A new eudesmane sesquiterpenoid lactone from Chloranthus japonicus

作　　者：房平磊[1,2] 刘海洋[1] 钟惠明[2] FANG Ping-Lei;LIU Hai-Yang;ZHONG Hui-Min(State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences Kunming 650204,China;College of Chemistry and Molecular Engineering,Qingdao University of Science and Technology,Qingdao 266042,China)

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明650204 [2]青岛科技大学化学与分子工程学院,青岛266042

出　　处：《中国天然药物》2012年第1期24-27,共4页

基　　金：supported by the National Natural Science Funding of China(No.81072543);the Key Project of Knowledge Innovation Project of CAS(No.KSCX2-EW-Q-10)~~

摘　　要：目的:研究银线草(Chloranthus japonicus)全株的化学成分;方法:利用各种色谱方法进行分离;通过各种光谱方法鉴定化合物结构;结果:从银线草分离得到1个新的倍半萜chlojaponilactoneA(1)和5个已知倍半萜:白术内酯III(2),neolitacumoneB(3),10α-hydroxy-1-oxoeremophila-7(11),8(9)-diene-8,12-olide(4),银线草内酯C(5)和银线草内酯H(6);结论:chlojaponilactoneA(1)为新的桉烷型倍半萜内酯,化合物3和4首次从该植物中分离得到。AIM： To study the chemical constituents of the whole plant of Chloranthusjaponicus. METHODS： Compounds were isolated and purified by column chromatography. Their structures were elucidated on the basis of spectroscopic methods. RESULTS： Six sesquiterpenoids were obtained and their structures were identified as chlojaponilactone A （1）, atractylenolide III （2）, neolitacumone B （3）, 10a-hydroxy-l-oxoeremophila-7（11）, 8（9）-diene-8, 12-olide （4）, shizukanolide C （5）, and shizukanolide H （6）. CONCLUSION： Compound 1 is a new eudesmane-type sesquiterpenoid lactone, and compounds 3 and 4 have been isolated from this species for the first time.

关 键 词：银线草 化学成分 倍半萜 桉烷型 

分 类 号：R284.1[医药卫生—中药学]