鸡血藤的化学成分(英文)  

Chemical constituents of Spatholobus suberectus

作　　者：唐任能[1,2] 曲晓波[1] 关树宏 徐萍萍 史洋洋 果德安 TANG Ren-Neng;QU Xiao-Bo;GUAN Shu-Hong;XU Ping-Ping;SHI Yang-Yang;GUO De-An(Changchun University of Chinese Medicine,Changchun 130117,China;Shanghai Research Centerfor Modernization of Traditional Chinese Medicine,National Engineering Laboratory for TCM Standardization Technology,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China)

机构地区：[1]长春中医药大学,长春130117 [2]中国科学院上海药物研究所上海中药现代化研究中心国家工程实验室,上海201203

出　　处：《中国天然药物》2012年第1期32-35,共4页

基　　金：supported by the grants from National Science&Technology Major Project"Key New Drug Creation and Manufacturing Program",China(Nos.2009ZX09308-005,2009ZX09311-001,2009ZX09502-020,2009ZX09304-002);Major Projects of Knowledge InnovationProgram of the Chinese Academy of Sciences(No.KSCX2-YW-R-166)~~

摘　　要：目的:研究鸡血藤的化学成分。方法:利用各种层析方法分离和纯化,并利用光谱学和理化性质来鉴定化合物结构。结果:从中分离得到17个化合物,分别鉴定为presteganeB(1),(2R,3R)-buteaspermanol(2),(+)-medioresinol(3),(2R,3R)-3,7-dihydroxyflavanone(4),benzeneethanol(5),4,7,2′-trihydroxy-4′-methoxyisoflavanol(6),naringenin(7),blumenolA(8),protocate-chuicacidethylester(9),liquiritigenin(10),7,4'-dihydroxy-8-methoxy-isoflavone(11),3,5,7,3',5'-pentahydroxyflavanone(12),pro-tocatechuicacid(13),glycyroside(14),8-methylretusin-7-O-β-D-glucopyranoside(15),3,3',4',5,6,7,8-heptahydroxyflavan(16),dul-cisflavan(17)。结论:所有的化合物均为首次从该植物中分离得到,其中1,3为首次从该属植物中分离得到。AIM： To investigate chemical constituents of Spatholobus suberectus Dunn. METHODS： Isolation and purification were carried out by column chromatographic methods. Compounds were characterized based on their physical characteristics and spectra data. RESULTS： Seventeen compounds were isolated from ethanol extract of S. suberectus. The structures were elucidated as prestegane B （1）, （2R, 3R）-buteaspermanol （2）, （＋）-medioresinol （3）, （2R, 3R）-3,7-dihydroxyflavanone （4）, benzeneethanol （5）, 4, 7, 2＇-trihydroxy-4＇-methoxyisoflavanol （6）, naringenin （7）, blumenol A （8）, protocatechuic acid ethyl ester （9）, liquiritigenin （10）, 7, 4＇-dihydroxy-8-methoxy-isoflavone （11）, 3, 5, 7, 3＇, 5＇-pentahydroxyflavanone （12）, protocatechuic acid （13）, glycyroside （14）, 8-methylretusin-7-O-β-D-glucopyranoside （15）, 3, 3＇, 4＇, 5, 6, 7, 8-heptahydroxyflavan （16）, and dulcisflavan （17）. CONCLUSION： All compounds are firstly isolated from the title plant and compounds 1, 3 were isolated from the Spatholobus genus for the first time.

关 键 词：鸡血藤 黄酮 化学成分 

分 类 号：R284.1[医药卫生—中药学]