感染因子与幼年特发性关节炎  

Infectious factors and Juvenile idiopathic arthritis

作　　者：胡国宏[1] 鹿玲[1] 

机构地区：[1]安徽医科大学第一附属医院儿科,合肥230022

出　　处：《国际免疫学杂志》2012年第1期54-57,共4页International Journal of Immunology

摘　　要：幼年特发性关节炎（JIA）是儿童时期常见的慢性风湿性疾病。本病病因及发病机理尚未完全阐明。目前认为本病与感染及自身免疫反应有关，可能是内源性和外源性抗原作用于具有遗传背景的易感个体产生或者触发自身免疫反应而导致自身组织损伤的结果，感染因子被认为是其潜在的致病因素。Juvenile idiopathic arthritis （JIA） is the most common chronic rheumatic disease of childhood. The pathogenesis of JIA is still not fully clarified, It is widely believed that JIA is correlated to infection and autoimmune reaction. It is possible that endogenous and .exogenous antigen affect susceptible individuals who have genetic backgrounds and induce autoimmune reactions. Therefore, infectious factors are considered as potential pathogenic factors.

关 键 词：感染因子 幼年特发性关节炎 

分 类 号：R725.9[医药卫生—儿科]