腹腔镜手术联合孕三烯酮治疗卵巢子宫内异症160例疗效观察  

CLINICAL OBSERVATION OF LAPAROSCOPIC OPERATION COMBINED WITH THE PREGNANCY THREE ALKENE KETONES IN TREATMENT OF OVARIAN ENDOMETRIOSIS AMONG 160 CASES

作　　者：吴清萍[1] 黄守国[1] 林卫琼[1] 

机构地区：[1]中南大学湘雅医学院附属海口医院妇产科,海口580208

出　　处：《现代预防医学》2012年第2期328-329,共2页Modern Preventive Medicine

摘　　要：[目的]观察腹腔镜术后联合孕三烯酮治疗卵巢子宫内膜异位症的疗效及安全性。[方法]选择2007年6月～2009年6月因卵巢子宫内膜异位症在某院行腹腔镜术的患者160例,随机分为2组:单纯腹腔镜手术组(对照组)80例;孕三烯酮组(实验组)80例,术后口服孕三烯酮2.5mg,2次/周,连用3～6个月。所有患者随访3～12个月。[结果]两组患者均通过腹腔镜完成手术,孕三烯酮组、单纯手术组有效率分别为84.21%和62.67%;复发率分别为6.58%和18.67%;不孕患者要求妊娠的受孕率分别为15.79%和5.56%,两组比较差异均有有统计学意义(P﹤0.05)。[结论]腹腔镜术后联合孕三烯酮治疗卵巢子宫内膜异位症疗效确切,能显著降低复发率,提高受孕率,且不良反应小,值得临床推广。[Objective]To observe the efficacy and safety of postoperative laparoscopic combined pregnancy three alkene ketones in treatment of ovarian endometriosis.[Methods]From 2007 June to June 2009 in our hospital,160 patients choice for ovarian endometriosis laparoscopic were randomly divided into 2 groups：pure laparoscopic operation group（control group）in 80 cases;the pregnancy three alkene ketone group（experimental group）in 80 cases,postoperative oral pregnancy three alkene ketone 2.5mg,2/W,once every 3 to 6 months.All patients were followed up for 3-12 months.[Results]Two patients were performed via laparoscopy operation,the pregnancy three alkene ketone group,simple operation rate in the group were 84.21% and 62.67%,respectively;recurrence rates were 6.58% and 18.67%,respectively;infertility patients require pregnancy pregnancy rates were 15.79% and 5.56%,respectively,and two groups compared difference to all have statistical significance（P﹤0.05）.[Conclusion]The laparoscopic surgery combined with pregnancy three alkene ketones in treatment of ovarian endometriosis curative effect was accurate,which can significantly decrease the recurrence rate and improve the pregnancy rate,and induce less side effect.This method is worthy to be popularized.

关 键 词：内膜异位症 腹腔镜手术 孕三烯酮 卵巢 

分 类 号：R711.75[医药卫生—妇产科学] R711.71[医药卫生—临床医学]