普外科Ⅰ类切口围手术期预防性抗菌药物使用调查分析  

Survey on the Usage of the Prophylactic Antibiotics Drugs with Type Ⅰ Incision Operation

作　　者：王飞[1] 俞建[1] 严伟[1] 

机构地区：[1]杭州市第一人民医院,杭州310006

出　　处：《中国现代应用药学》2012年第1期77-79,共3页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的了解普外科I类切口手术围手术期预防性抗菌药物使用现状,提高临床合理用药水平。方法采用回顾性调查方法,随机抽取2010年1月～2月份普外科I类切口手术出院病历52份,对围手术期用药指征、抗菌药物品种选择、用药时间和药物利用指数等方面进行分析。结果 52例I类切口手术病历全部使用抗菌药物,使用频度较高的药物为依替米星、头孢米诺钠和氨苄西林/舒巴坦,42.31%的患者用药时间≤3 d,32.69%的患者二联用药,使用频度较高的氨苄西林/舒巴坦和头孢唑啉的药物利用指数(DUI)>1。结论普外科I类切口手术围手术期抗菌药物的使用尚需进一步规范。OBJECTIVE To investigate and analyze the application of prophylactic antibiotics with type I recision operation in hospital so as to provide a further guidance for rational drug use. METHODS Case history of 52 cases with type I incision operation were randomly retrieved, whose data concerning drug categories, duration of medication, drug combination, DUI, ect were analysed. RESULTS All of the 52 cases were given the antibacterial drugs in perioperative period, the first three kinds were etimicin, cefminox sodium, latamoxef sodium, ampicillin-sulbactam. 42.31% of cases were treated three days. The rate of antibiotics combination using was 32.69%. ampicillin-sulbactam, cefazolin use indexs （DUI） were 〉1. CONCLUSION Irrational antibiotic prophylaxis in type I incision perioperative period exists, it is suggested that antibiotic prophylaxis in type I incision perioperative period should be further strengthened to supervise and management.

关 键 词：Ⅰ类切口 围手术期 抗菌药物 预防用药 

分 类 号：R978.1[医药卫生—药品]