非淋病性尿道炎患者解脲脲支原体耐药性分析  

Antimicrobial resistance of Ureaplasma urealyticum from patients with nongonococcal urethritis

作　　者：李俊 

机构地区：[1]五峰土家族自治县人民医院检验科,湖北五峰443400

出　　处：《中华医院感染学杂志》2012年第1期208-209,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解非淋病性尿道炎患者解脲脲支原体(Uu)感染状况及耐药性,为临床医师抗感染治疗提供试验依据。方法无菌采集1342例非淋病性尿道炎患者的生殖道分泌物标本,采用珠海迪尔生物有限公司生产的试剂盒进行支原体属培养和药敏试验。结果 Uu阳性检出率为31.9%,Uu对12种抗菌药物的药敏结果显示,对氟喹诺酮类抗菌药物环丙沙星和氧氟沙星敏感率最低为9.3%、15.9%,对交沙霉素、四环素、多西环素、克拉霉素、米诺环素敏感率均>70.0%。结论 Uu对常用抗菌药物已产生了不同程度的耐药性,因此,必须提高支原体属培养的送检率,这对临床医师及时诊断、提升疾病治愈率非常重要。OBJECTIVE To investigate the infection status and antimicrobial resistance of Ureaplasma urealyticurn （Uu） from patients with nongonococcal urethritis and provide experimental evidence for the clinical anti-infection treatment. METHODS A total of 1342 cases of genitourinary tract specimens from patients with nongonoeoecal urethritis were collected by aseptic technique. The Uu cultivation and drug susceptibility testing were performed using kit produced by Zhuhai DL medical Co, Ltd. RESULTS The total positive detection rate of Uu was 31.9%. The susceptibility test results indicated that susceptibility rate of quinolones, such as ciprofloxacin （9. 30%） and ofloxacin （15. 9%） were the lowest. The susceptibility rates of Josarnyein, tetracycline, doxycycline, clarithromycin and rninocycline were all above 70%. CONCLUSION The varying antimicrobial resistance to different commonly used antibiotics occurs in Uu. Therefore, it is important to increase the rate of sample delivery for Uu assays for timely clinical diagnosis and increasing the cure rate.

关 键 词：非淋病性尿道炎 泌尿生殖道 感染 解脲脲支原体 药敏试验 

分 类 号：R375[医药卫生—病原生物学]