诱导拆分法合成D(-)-酒石酸的工艺研究  

Research of D(-)-tartaric Acid Synthesis by Induction Split

作　　者：罗序燕[1] 夏美林[1] 徐李广 

机构地区：[1]江西理工大学冶金与化学工程学院,江西赣州341000 [2]宁波万华聚氨酯有限公司,浙江宁波315000

出　　处：《广州化工》2012年第1期73-75,共3页GuangZhou Chemical Industry

摘　　要：介绍了诱导拆分法合成D(-)-酒石酸的合成工艺、操作过程和控制条件,发现拆分的最优条件为:在28℃放晶种,缓慢冷却到有晶体开始析出1分钟后立即过滤,即可将外消旋酒石酸铵钠拆分成左旋酒石酸铵钠和右旋酒石酸铵钠,再利用置换反应就能得到D(-)-酒石酸。旋光度为[α]2D0-12.19°(c=20,H2O),拆分率大有提高,为46.5%。The synthesis method,operation process and control condition of induction split D（-）-tartaric acid with induction split were introduced,and found that the optimal conditions for resolution were that in the 28 ℃ put the seed,slow cooling to have crystal,and 1 min separation immediately after the filter,and the filter can spin tartaric acid and ammonium away sodium left spin tartaric acid sodium ammonium and a right-handed,using ammonium tartaric acid sodium placement response can get D（-）-tartaric acid.The optical rotations was [α]20D=-12.19 °（c=20,H2O）,and the resolution ratio was greatly enhanced for 46.5%.

关 键 词：诱导拆分 晶种 合成 转化 

分 类 号：O621[理学—有机化学]