儿童特发性间质性肺炎12例临床分析  

Clinical analysis of 12 cases with idiopathic interstitial pneumonia in children

作　　者：湛洁谊[1] 丘红英[2] 陈爱欢[3] 黄穗[1] 孙丽红[3] 

机构地区：[1]广州医学院第一附属医院儿科,广东广州510120 [2]广州医学院第一附属医院放射科,广东广州510120 [3]广州呼吸疾病研究所,广东广州510120

出　　处：《中国儿童保健杂志》2012年第1期88-89,95,共3页Chinese Journal of Child Health Care

摘　　要：【目的】探讨儿童特发性间质性肺炎的临床及预后,为临床治疗提供依据。【方法】回顾性分析12例儿童特发性间质性肺炎的临床、影像、治疗反应和预后。【结果】主要症状为慢性咳嗽、呼吸困难,胸部高分辨CT显示:磨玻璃阴影、斑片状模糊影、线条状、网状阴影及蜂窝状改变。肺功能有限制性通气功能和弥散障碍。以激素、甲氨蝶呤、乙酰半胱氨酸的综合治疗对大部分儿童特发性间质性肺炎有一定效果。【结论】激素是治疗特发性间质性肺炎的首选药物,胸部CT显示病变呈磨玻璃样者激素疗效较好,而网格影或者蜂窝状改变疗效欠佳。【 Objective 】 To investigate the clinical characteristics and prognosis of idiopathic interstitial pneumonias（IIPs） in children.【 Method 】 A retrospective analysis was held on the pediatric patient＇s clinical meterials of 12cases diagnosed as IIP.【 Results 】 The main symptoms were chronic cough,progressive dyspnea,high resolution computed tomography indicated ground-glass opacities,frosted,reticulate and honeycomb.Pulmonary function test was consistent with restrictive impairment and impaired gas exchange.Use of steroids,Methotrexate,Acetylcysteine Granules and oxygen was partially effective.【 Conclusion 】 Steroid is the first choice for IIPs.Ground-glass opacities in radiology has a favorable reaction to glucocorticoid therapy and a better prognosis as compared to the honeycomb in radiology.

关 键 词：特发性间质性肺炎 儿童 治疗 

分 类 号：R722.1[医药卫生—儿科]