次血红素六肽对纳米金诱导线虫热激损伤的保护作用  

DhHP-6 Protection of Caenorhabditis elegans from Heat Shock Injury Induced by Au Nanoparticles

作　　者：郭常闰[1] 关树文[1] 黄磊[1] 张超[1] 董彪[2] 宋宏伟[2] 王丽萍[1] 

机构地区：[1]吉林大学生命科学学院,长春130012 [2]吉林大学电子科学与工程学院,长春130012

出　　处：《吉林大学学报（理学版）》2012年第1期153-156,共4页Journal of Jilin University:Science Edition

基　　金：国家高技术研究发展计划863项目基金(批准号:2007AA032314)

摘　　要：通过考察Au纳米球壳对野生型秀丽隐杆线虫的光热转换作用,建立一种新型的秀丽线虫热激损伤模型.实验结果表明,在纳米金浓度为30μmol/L,红外光强为3 W/cm2,照射8 min的热激条件下加入次血红素六肽对线虫有保护作用.Using the light-heat conversion induced by Au nanoparticles,we created a new experimental method of heat-shock for Caenorhabditis elegans.DhHP-6 is a mimetic peroxidase designed and synthesised by our laboratory.C.elegans was incubated with Au nanoparticles at the concentration of 30 μmol/L and exposed to the infrared lights at a intensity of 3 W/cm2 for 8 min.The results showed that DhHp-6 had protective effect on the C.elegans in this heat-shock conditions.

关 键 词：Au纳米球壳 秀丽隐杆线虫 热激 次血红素六肽 

分 类 号：Q613[生物学—生物物理学]