模板剂对共沉淀法合成纳米羟基磷灰石粉体形貌的影响  

Influence of Templates on Morphology of Nano-Hydroxyapatite Synthesized by Co-Precipitation Method

作　　者：孙艳荣[1] 范涛[1] 刘峰[1] 马利国[1] 汪长安[2] 

机构地区：[1]北华航天工业学院材料工程系,河北廊坊065000 [2]清华大学材料科学与工程系,新型陶瓷与精细工艺国家重点实验室,北京100084

出　　处：《硅酸盐学报》2012年第1期90-94,共5页Journal of The Chinese Ceramic Society

基　　金：河北省自然科学基金(E2011409001);新型陶瓷与精细工艺国家重点实验室(清华大学)开放课题(KF09011);北华航天工业学院科研基金(KY-2009-01-B)资助项目

摘　　要：采用共沉淀法,以Ca(NO3)2.4H2O和(NH4)2HPO4为反应体系,分别添加硫酸软骨素、琼脂糖和天门冬氨酸作为模板剂,引入生物矿化作用,合成了不同形貌的纳米羟基磷灰石粉体。采用X射线衍射法和透射电子显微镜分析了合成产物的晶相结构和粉体形貌。结果表明3种模板剂作用下合成的样品都是纯相的纳米羟基磷灰石。在添加硫酸软骨素(≥0.2%,质量分数,下同)或琼脂糖(1.0%)的条件下,当反应体系钙磷比(钙与磷的摩尔比)为1.67,反应pH值为11.0,纳米羟基磷灰石的形貌分别是梭形短片状和纤维丝状。当天门冬氨酸浓度为2.0%时,若反应体系钙磷比为1.62,反应pH值为10.0,其形貌为类球状;若反应体系钙磷比为1.72,反应pH值为8.5,其形貌则为片状。Nano-hydroxyapatite powders with different morphology were synthesized by the co-precipitation method,in the preparing process Ca（NO3）2？4H2O and（NH4）2HPO4 were used as reagents,and chondroitin sulfate,agarose and aspartic acid were added re-spectively as a template under biomineralization.The structure and morphology of the prepared powders were characterized by means of X-ray diffraction and transmission electron microscope.The results indicated that the three templates resulted in pure nano-hydroxyapatite powders.When the ratio of Ca to P in the reaction was 1.67 and the pH was 11.0,the morphology of na-no-hydroxyapatite seemed to be fusiform flake and fiber-like with the presence of chondroitin sulfate（≥0.2%,in mass,the same below） and agarose（1.0%）,respectively.When the concentration of aspartic acid is 2.0%,quasi-globule（mole ratio of Ca to P,n（Ca）/n（P）=1.62,pH=10.0） and plate-like（n（Ca）/n（P）=1.72,pH=8.5） morphologies were obtained,respectively.

关 键 词：羟基磷灰石 模板剂 共沉淀法 生物矿化 

分 类 号：TQ174[化学工程—陶瓷工业]