外感发热中医急诊退热方案的研究——附906例临床资料分析  

Research on Antipyretic Project of TCM Emergency Care for Exogenous Fever with Analysis of 906 Clinical Cases

作　　者：奚肇庆[1] 刘清泉[2] 姜树民[3] 张晓云[4] 于强[5] 关继华 周建中[7] 罗翌[8] 赵为民[9] 魏江磊[10] 梅建强[11] 张念志[12] 孙伯青[13] 谭善忠[14] 葛爱琴 齐文升[16] 孙菊光 杜梁枫 郑艳[19] 余衍亮[1] 陈海铭[3] 陈分乔[11] 余婉蓉[19] 张丽[19] 耿连艺[19] 

机构地区：[1]江苏省中医院,江苏南京210000 [2]北京中医药大学附属东直门医院,北京100000 [3]辽宁中医药大学附属医院,辽宁沈阳110000 [4]成都中医药大学附属医院,四川成都610000 [5]天津市南开医院,天津300000 [6]新疆维吾尔自治区中医院,新疆乌鲁木齐830000 [7]江苏省南京市中医院,江苏南京210000 [8]广东省中医院,广东广州510000 [9]长春中医药大学附属医院,吉林长春130000 [10]上海中医药大学附属曙光医院,上海200000 [11]河北省中医院,河北石家庄050000 [12]安徽中医学院附属医院,安徽合肥230000 [13]江苏省昆山市中医医院,江苏昆山215300 [14]东南大学附属南京市第二医院,江苏南京210000 [15]西藏自治区拉萨市墨竹工卡县人民医院,西藏拉萨850000 [16]中国中医科学院广安门医院,北京100000 [17]江苏省徐州市中医院,江苏徐州215000 [18]江苏省无锡市中西医结合医院,江苏无锡214000 [19]南京中医药大学,江苏南京210000

出　　处：《中国中医急症》2012年第1期1-3,76,共4页Journal of Emergency in Traditional Chinese Medicine

基　　金：国家中医药行业重大科研专项(200807041)

摘　　要：目的观察国家中医药管理局重点专科中医急诊外感发热方案治疗上呼吸道感染退热的疗效。方法采用多中心、队列试验的设计方法,906例患者中上呼吸道感染863例,甲型H1N1流感43例,分别用麻黄汤加味、葛根汤加减治疗风寒证141例,中成药双黄连口服液、疏风解毒胶囊治疗风热证178例,清肺消炎饮加减、上感颗粒治疗卫气同病证587例。结果起效时间:4h内即刻退热人数比26.15%～100.00%。解热时间:4h内治愈率17.69%～91.67%;72h治愈率89.57%～100%。临床症状改善率达80%以上。结论各协作组验证方案、方药,对上呼吸道病毒感染性发热有较好的退热和缓解外感发热伴随症状的作用。Objective： To observe the antipyretic project of exogenous fever on the fever caused by upper respiratory tract infection in TCM emergency care of state administration of TCM.Methods： A multi-centers,cohort study was conducted.A total of 906 patients including 863 cases of upper respiratory tract infection and 43 cases of influenza A H1N1 subtype were separately treated by Mahuang Decoction and Gegen Decoction for 141 cases of wind and cold syndrome,Shuanghuanglian Oral Formulation and Shufengjiedu Capsule for 178 cases of ind and warm syndrome,Qingfeixiaoyan Decoction and Shanggan Granule for 578 cases of Wei and Qi syndrome.Results： On-set time： the instantly heat-reducing rate within 4h was between 100.00% and 26.15%.Antipyretic time： the rate of body-temperature recovering to normal within 4h was between 17.69% and 91.67%.The curative rate within 72h was between 89.57% and 100%.The improvement rate of clinical symptoms was above 80%.Conclusion： Clinical projects and medicine in each cooperation group have well efficacy on heat-reducing and accompanying symptoms relieving of viral upper respiratory tract infection.

关 键 词：外感发热 上呼吸道感染 甲型H1N1流感 多中心临床试验 急诊协作组治疗方案 

分 类 号：R254.9[医药卫生—中医内科学]