新生儿缺血缺氧性脑病对早产儿排尿方式的影响  

A study on voiding pattern in preterm newborns with hypoxic-ischemic encephalopathy

作　　者：文建国[1] 晋朝娜 杨黎[1] 王亚仑[1] 陈燕[1] 吕宇涛[1] 崔林刚[1] 张茜 

机构地区：[1]郑州大学第一附属医院小儿尿动力学中心、泌尿外科,河南省高等学校临床医学重点学科开放实验室,450052 [2]新生儿重症监护室

出　　处：《中华小儿外科杂志》2012年第1期35-37,共3页Chinese Journal of Pediatric Surgery

摘　　要：目的 探讨新生儿缺血缺氧性脑病（HIE）对早产儿排尿方式的影响。方法选取出生后4～15d确诊为新生儿缺血缺氧性脑病早产儿48例，男34例，女14例，孕（32．1±0．7）周，出生时体重（2．5±0．3）kg。选取同期出生后4～15d无缺血缺氧性脑病的33例早产儿为对照组，男22例，女11例，孕（32．3±1．4）周，出生时体重（2．4±0．5）kg。记录4h（早上8点～10点）排尿情况，包括排尿量、残余尿量、排尿次数等参数，同时记录饮奶量、液体输入量及摄入时间，液体摄入量按标准进行。结果共记录了248次排尿，其中HIE组136次，对照组112次。HIE组排尿量和排空比例分别为（14．8±8．3）ml和11．6oA，均显著小于对照组[（16．5±9．2）ml和24．3％]；而HIE组的排尿次数、平均残余尿量分别为（2．8±1．1）次、（1．5±1．3）ml，对照组为（3．3±1．2）次、（1．7±0．9）ml，两者之间的差异无统计学意义。结论缺血缺氧性脑病可使早产儿出现一定程度排空和储尿障碍，表现为每次排尿量及排空比例降低。Objective To investigate the poxic-ischemic encephalopathy （HIE）. Methods voiding pattern in preterm neonates affected by hy- A total of 81 preterm newborns aged 4 to 15 days at The First Affiliated Hospital of Zhengzhou University from March to October 2010 were included in this study,48 of them affected by HIE （32.1 ±0. 7 weeks of gestation） with weight of 2. 5 ± 0. 3 kg, the other 33 preterm were normal （32. 3± l. 4） weeks of gestation,body weight： 2. 4 ± 0. 5 kg）. The voided volume,post void residual （PVR） volume, voiding frequency per 4 hours as well as the quantity of milk and liquid intake within the same time schedule for 4 hours from 8AM to 2AM were recorded. The liquid intake was given according to standard protocol. Results A total of 248 times of voiding were recorded. Voided volume and bladder empty percentage was significant lower in newborn with HIE comparing to controls [ （14. 4 ± 8. 3） ml vs. （ 16. 5± 9.2） ml and 11.6 % vs. 24. 3 %, （P〈0.05）, respectively, whereas voiding frequency, PVR volume showed no significant difference. Conclusions The difference of voiding patterns between newborn with HIE and controls indicates HIE has a significant effect on the bladder storage and voiding function.

关 键 词：缺氧缺血 脑 排尿 

分 类 号：R722[医药卫生—儿科]