血压变异性和容积脉搏波特征参数变异性的关联分析  

Study of the correlation between the blood pressure variability and the variabilities in photoplethysmography parameters

作　　者：车大莹[1,2] 杨平[1,2] 张元亭[1,2] 

机构地区：[1]中国科学院健康信息学重点实验室,深圳518055 [2]中国科学院深圳先进技术研究院生物医学与健康工程研究,深圳518055

出　　处：《国际生物医学工程杂志》2011年第6期321-324,330,共5页International Journal of Biomedical Engineering

基　　金：国家重点基础研究发展计划（973计划）基金资助项目（2010cB732606）;广东省引进创新科研团队资助项目;国家自然科学青年基金项目（61002002）

摘　　要：目的分析血压变异性和容积脉搏波特征参数变异性的相关性，确定相关性较好的参数，为利用容积脉搏波特征参数的变异性来估计血压变异性提供理论依据。方法同步连续采集运动前后19个样本的容积脉搏波信号和血压信号，根据容积脉搏波信号的波形特征，提取8个特征参数，利用皮尔森相关系数分析血压变异性和容积脉搏波特征参数变异性在时域的相关性。结果从容积脉搏波所提取的8个特征参数中，容积脉搏波主波高度的每搏变化与收缩压每搏变异性运动前后相关系数分别为0．76和0．75；波谷到降中峡时间的每搏变化与收缩压每搏变异性运动前后相关系数分别为0．74和0．78。结论容积脉搏波的主波高度的每搏变异性与每搏血压变异性变化之间存在较高的相关关系，可用于近似估计血压变异性。上述发现表明单独基于容积脉搏波的特征变异性来无创连续监测血压变异性具有理论可能性。Objective To investigate the correlation between blood pressure variability and variabilities of some feature variables extracted from photoplethysmography （PPG） signal. Methods Continuous blood pressure （BP） and PPG signal were collected simultaneously from 19 healthy subjects under rest and after exercise. Eight feature variables were extracted from the PPG signal. The relationship between the beat-to-beat variability of BP and feature variables extracted from PPG were quantified by calculating Person＇ s correlation coefficient. Results The variability of the amplitude of PPG was highly correlated with systolic BP variability both under rest （0.75） and after exercise （0.76）. Meanwhile, the correlations between systolic BP variability and the variability of the time from the trough to the dicrotic north were 0.74（under rest） and 0.78（after exercise）. Conclusion The amplitude variability of PPG is highly correlated with systolic BP variability and can be potentially used for monitoring BP variability.

关 键 词：血压变异性 脉搏波 相关性分析 

分 类 号：R544.1[医药卫生—心血管疾病]