工程软骨支架的临床应用研究进展  

Research development of scaffolds for engineering cartilage

作　　者：蒿俊行[1] 郝剑 朴哲[1] 李继海[1] 

机构地区：[1]天津市南开医院骨科,300100

出　　处：《国际生物医学工程杂志》2011年第6期380-382,I0002,共4页International Journal of Biomedical Engineering

摘　　要：移植工程软骨修复软骨损伤是目前较为理想的治疗方法，构建工程软骨需要种子细胞和支架材料，支架材料的性能对工程软骨的生物特性有重要影响。讨论支架材料的研究进展，比较不同支架材料的工程软骨的临床应用结果，对进一步改善工程软骨的生物学性能有重要意义。结合近年来工程软骨支架的研究和临床应用情况作一综述和展望。Transplantation of engineering cartilage is a better choice for the treatment of articular cartilage lesions. Constructing engineering cartilage needs seeded ceils and scaffold materials. The property of scaffold materials has a great influence on the biomechanical features of engineering cartilage. A variety of materials can be used for constructing engineering cartilaginous framework. Exploring the research development of scaffold materials and comparing the effects of their clinical applications is of great significance for further improvement of biomechanical characteristics of the engineering cartilage.

关 键 词：工程软骨 软骨修复 支架材料 软骨损伤 

分 类 号：R318.08[医药卫生—生物医学工程] Q813[医药卫生—基础医学]