蠲痛饮对子宫内膜异位症白兔腹腔液IL-6的影响  

Effect of Level of IL-6 in Ascitic Fluid to White Rabbit of Juantongyin in Treating Endometriosis

作　　者：林艳明[1] 李莉[2] 庞广福[1] 

机构地区：[1]右江民族医学院,广西百色533000 [2]广西中医学院瑞康医院,广西南宁530011

出　　处：《辽宁中医药大学学报》2012年第2期73-75,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：广西科学研究与技术开发计划基金项目(桂科攻0993003D-19);广西教育厅科研课题(200911MS192)

摘　　要：目的:研究中药蠲痛饮对子宫内膜异位症新西兰大耳白兔腹腔液IL-6的干预作用。方法:将新西兰大耳白兔随机分成空白对照组、模型组、蠲痛饮高剂量组、中剂量组、低剂量组及达那唑组,采用白兔自体内膜子宫异位症造模方法,通过ELISA法检测各组白兔腹腔液IL-6含量,并进行统计学分析比较。结果:模型对照组腹腔液中IL-6含量较空白组有显著增高(P<0.01),蠲痛饮高剂量组、中剂量组、低剂量组能降低腹腔液中IL-6中的含量,且以高剂量组效果显著,与模型对照组比较,有统计学差异(P<0.05)。结论:蠲痛饮可能是通过降低子宫内膜异位症白兔腹腔液IL-6含量而对子宫内膜异位症产生治疗作用。Objective ： Resrarch On intervention role of the level of IL-6 in ascitic fluid to New Zealand big-eared white rabbit of Juantongyin in treating endometriosis. Methods：Rabbits were randomly allite in 6 groups：normal groug, model groug, high Juantongyin, medium Juantongyin, low Juantongyin and Danazol group. EWT was surgically induced in the femal New Zealand rabbits first. Obsreve the effect of IL-6 of peritoneal fliud through ELISA test and the statistical analysis companison. Results ： There are significantly higher in the level of IL-6 of model groug than of the nornal groug. High Juantongyin, medium Juantongyin, low Juantongyin of peritoneal fluid can reduce the content of IL-6, and in the high Juantongyin effect significantly, compared with model group, statistically significant （ P〈0.05 ）. ConcIusion ： Juantongyin may be by lowering the level of IL-6 in ascitic fluid of white rabbit for endomtriosis produce treatment function.

关 键 词：蠲痛饮 子宫内膜异位症 IL-6 白兔 

分 类 号：R711.71[医药卫生—妇产科学]