甲状旁腺腺瘤引发棕色瘤的影像学诊断  

Brown tumors caused by parathyroid adenoma imaging diagnosis

作　　者：梁鹏[1,2] 汪卫中[1] 赵冬青[1] 冯霞[2] 梁万琴[1] 

机构地区：[1]解放军第474医院影像中心,乌鲁木齐830013 [2]南方医科大学南方医院影像诊断中心,广州510515

出　　处：《医疗装备》2012年第1期24-26,共3页Medical Equipment

摘　　要：目的:分析甲状旁腺瘤引发的骨病棕色瘤X线、CT影像学表现与相关临床特点,提高诊断准确性。方法:回顾性分析经手术病理证实的4例甲状旁腺瘤引发的棕色瘤的影像资料。结果:4例病人中,所有X线检查均可见全身多骨广泛性骨质疏松,多发局限性囊状骨质破坏。3例不同部位病理骨折;1例颅骨内、外板边缘模糊、密度减低,呈磨玻璃样并伴有颗粒样骨吸收区;1例病灶与脑膜广泛相连且穿破板障达皮下,并向下累及蝶窦、筛窦及鼻道;1例骨质破坏区伴有软组织肿块。结论:甲状旁腺功能亢进好发于女性,平均年龄56～62岁;发病隐匿,大约12%～50%没有临床症状;肾受累、肾结石大约占4%～30%;骨受累大约占14%～20%;甲旁亢的血清钙增高、血清磷降低、碱性磷酸酶增高,尿钙及尿磷均增高。一些X线表现并无特异性,但将临床及X线征象结合起来则易于诊断。Objective：To analyze parathyroid tumors caused by brown tumor of bone X-ray,CT imaging and related clinical features,improve diagnostic accuracy.Methods A retrospective analysis of pathologically confirmed four cases of brown tumors caused by parathyroid adenoma image data,where X-ray examination of three cases,CT examination 4 cases,MRI examination in 1 case.Results Four patients,2 males and 2 females,aged 33 to 67 years,X-ray examination in all cases were seen extensive bony body osteoporosis,the limitations of multiple cystic bone destruction.Three cases in different parts of the pathological fracture;one case the skull,the outer plate edge blur,reduce the density,and was ground-glass-like particles associated with bone resorption areas;one case of extensive lesions with meningeal perforation plate is connected to and under the barrier Bag,to involved under the sphenoid sinus,ethmoid sinus and nasal passages;one case of bone destruction associated with soft tissue mass.Conclusion Hyperparathyroidism occurs in women,average age 56 to 62 years of age;incidence of occult,about 12% to 50% without clinical symptoms;renal involvement,kidney stones account for about 4% to 30%;bone involvement,accounting for about 14 % to 20%;hyperparathyroidism increased serum calcium,serum phosphorus decreased,alkaline phosphatase,urinary calcium and phosphorus were increased.Some X-ray is not specific,but the clinical and X-ray findings together is easy to diagnose.

关 键 词：甲状旁腺腺瘤 棕色瘤 X线计算机 

分 类 号：TH774[机械工程—仪器科学与技术]