盐酸特比萘芬阴道泡藤片联合乳杆菌活菌治疗复发性外阴阴道假丝酵母菌病57例临床观察  

The Effects of Terbinafine Hydrochloride Vaginal Effervescent Tablets Combined with Live Lactobacillus Capsule on Recurrent Vulvovaginal Candidasis

作　　者：戈静[1] 叶珂帆[1] 

机构地区：[1]云南省第一人民医院(昆明医学院附属昆华医院)妇科,云南昆明650032

出　　处：《中国皮肤性病学杂志》2012年第1期33-35,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的观察盐酸特比萘芬阴道泡藤片联合乳杆菌活菌治疗复发性外阴阴道假丝酵母菌病(RVVC)的临床疗效。方法将164例RVVC患者随机分为3组,治疗组(57例)予盐酸特比萘芬阴道泡藤片联合乳杆菌活菌胶囊治疗,对照1组(50例)仅予盐酸特比萘芬阴道泡藤片治疗,对照2组(57例)仅予硝酸咪康唑阴道胶囊治疗。3组患者均随访1年。结果 1年后,治疗组、对照1组和对照2组有效率分别为89.47%,80.00%,73.68%,复发率分别为10.00%,25.64%和26.19%,3组的有效率和复发率比较,差异均有统计学意义(P均<0.05)。结论盐酸特比萘芬阴道泡藤片联合乳杆菌活菌治疗RVVC的疗效好,复发率低。Objective To observe effects of terbinafine hydrochloride vaginal effervescent tablets combined with living preparation of lactobacillus on recurrent vulvovaginal candidasis （RVVC）. Methods One hundred and sixty-four patients of RVVC were randomly divided into treatment group treated with terbinafine hydrochloride vaginal effervescent tablets plus live lactobacillus capsule, control group 1 treated with terbinafine hydrochlo- ride vaginal effervescent tablets alone and control group 2 treated with miconazole nitrate vaginal capsules, observing the recurrence rate after treatment one year. Results After one year,the effective rate was 89. 47% ,80.00% ,73.68% and recurrence rate wasl0.00% ,25.64% ,26.19% in treatment group, control 1 and 2 group respectively. There was a singnificant difference between treatment group and the two control groups （p 〈 0.05 ）. Conclusion The combination of terbinafine hydrochloride vaginal effervescent tablets with living preparation of lactobacillus capsule showed satisfactory efficacy and low recurrence rate in treat- ment recurrent vulvovaginal candidasis.

关 键 词：复发性外阴阴道假丝酵母菌病 盐酸特比萘芬阴道泡藤片 乳杆菌活菌胶囊 

分 类 号：R711.31[医药卫生—妇产科学]