脑死亡供肾肾移植受者的近期状况分析  

Short-term outcomes of renal transplant recipients receiving kidney grafts from brain-death donors

作　　者：汪帮琦 朱云松 聂海波 赵永斌 胡卫列 

机构地区：[1]解放军下尿路疾病诊治中心,解放军广州军区器官移植中心,广东省广州市510010

出　　处：《中国组织工程研究与临床康复》2011年第53期9917-9920,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：国家自然科学基金项目(30872577);广东省科技计划项目(2011B031800199)~~

摘　　要：背景:供者短缺严重限制了肾移植的发展,脑死亡供肾在一定程度上缓解了供肾短缺的问题。目的:比较脑死亡供肾与尸体供肾肾移植患者移植后短期预后情况,初步探讨脑死亡供者在肾移植临床应用中的安全性。方法:回顾性分析肾移植90例患者移植过程中和移植后情况,其中80例供者为尸体供肾,10例为脑死亡供肾,比较两组受者移植中出血量、手术时间、移植后移植肾功能恢复情况、各种并发症的发生率及移植后近期生存情况(围手术期、移植后6个月)的差异。结果与结论:两组间移植时间、移植过程中出血量比较差异无显著性意义,移植后1,6个月生存率及移植后并发症的发生率比较,差异亦无显著性意义。说明脑死亡供肾与尸体供肾肾移植患者移植后早期预后无明显差异,安全可靠。BACKGROUND： The shortage of donors has severely limited the development of renal transplantation. However, brain-death donors can alleviate the problem of renal transplantation donor shortage to some extent. OBJECTIVE： To compare the short-term outcomes of renal transplantation recipients receiving kidney grafts from brain-death and cadaveric brainstem dead donors and evaluate the safety of kidney grafts from brain-death donors. METHODS： A total of 90 patients receiving renal transplantation were retrospectively analyzed, including 10 patients receiving kidney graft from brain-death donors and 80 with grafts from cadaveric brainstem dead donors. The operative time, bleeding volume, postoperative complications and short-term survival were compared between the two groups. RESULTS AND CONCLUSION： The operative time, bleeding volume, postoperative complications and short-term survival showed no significant differences between the two groups. The short-term outcome of recipients receiving kidney grafts from brain-death donors is similar to that of recipients receiving grafts from cadaveric brainstem dead donors, indicating the safety of clinical use of the kidney grafts from brain-death donors.

关 键 词：肾移植 供者 脑死亡供肾 尸体供肾 预后 

分 类 号：R617[医药卫生—外科学]