微生物嗜盐酶盐适应性的分子结构基础研究  

Molecular Structural Basis of Microbial Halophilic Enzymes Related to Their Haloadaptation

作　　者：阎松[1,2] 陈雷[3] 林秀坤[1] 

机构地区：[1]中国科学院海洋所实验海洋生物学重点实验室,青岛266071 [2]大连交通大学环境与化学工程学院,大连116028 [3]哈尔滨工业大学(威海)海洋学院,威海264209

出　　处：《中国细胞生物学学报》2012年第1期91-97,共7页Chinese Journal of Cell Biology

基　　金：中国博士后基金(No.20100471579)资助项目~~

摘　　要：由高盐环境中生长的微生物里分离出的嗜盐酶在高盐度下仍然具有催化活性,工业上具有良好的应用前景。一些嗜盐酶已被克隆纯化出来,它们的分子结构特点也已经被广泛研究。该文从嗜盐酶的蛋白质序列和结构特征等方面综述了嗜盐酶嗜盐的分子结构基础研究进展,分析了存在的问题并对未来工作提出了展望。研究嗜盐酶盐适应性的分子基础,可以为新的功能蛋白的发展和鉴定提供依据。Halophilic enzymes are isolated from microorganisms lived in the environment with high salt concentration, and this kind of enzyme only functions under high salt conditions. Halophilic enzymes have beenconsidered to have a variety of industrial applications due to their tolerance on salt. Some halophilic enzymes have been cloned and purified and their molecular structural properties have been widely studied. In the present review,the recent progresses of molecular structural basis of halophilic enzymes related to halophilic characteristics are presented. Some questions and the prospects of future studies are also discussed. This review will contribute to afurther understanding of the molecular basis of haloadaptation in halophilic enzymes and will be helpful for devel- oping and identifying functional novel proteins.

关 键 词：嗜盐酶 盐适应性 分子结构基础 

分 类 号：Q93[生物学—微生物学]