春季花粉浓度对过敏性鼻炎患者的影响  

Effects of spring pollen concentration on allergic rhinitis subjects in Beijing

作　　者：欧阳昱晖[1,2] 范尔钟[1,2] 李颖[1,2] 曹飞飞[2] 贺飞[1,2] 顾英[2] 张伟[1,2] 张德山[3] 张罗[1,2] 

机构地区：[1]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),北京100730 [2]北京市耳鼻咽喉科研究所,北京100005 [3]北京市气象局,北京100089

出　　处：《中国耳鼻咽喉头颈外科》2011年第12期628-630,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：国家杰出青年科学基金(81025007)

摘　　要：目的探讨春季花粉浓度及其对过敏性鼻炎(AR)患者的发病时间及临床症状的影响。方法使用Durhum花粉采集仪监测北京城区2011年3～6月花粉的浓度和种属;过敏原皮肤点刺试验筛选春季花粉过敏的AR患者,分为单纯花粉过敏患者组(单纯组)及花粉并常年性过敏原过敏患者组(混合组),两组患者均予症状评估,并分析其发病时间与花粉浓度的相关性。结果春季花粉量呈现2个高峰,分别在3月25日～4月9日和4月24日～5月24日。日花粉浓度最高达187粒/1000 mm2。单纯组的症状开始时间与春季花粉浓度有相关性。单纯组鼻眼痒的症状较混合组严重(P<0.01),混合组鼻堵症状评分高于单纯组(P<0.01)。结论花粉浓度对AR患者的发病有重要影响,空气中花粉含量监测对AR患者具有重要的预防和治疗意义。OBJECTIVE To evaluate the effect of spring pollen concentrations on clinical manifestation in allergic rhinitis patients.METHODS Durhum sampler was used to detect pollen concentration and species from March to June in 2011 in Beijing.The patients with spring pollen allergic rhinitis were divided into pure pollen allergic rhinitis group（pure group）and pollen combined perennial allergens allergic rhinitis group（combined group）.Symptoms score of patients were assessed,and the correlation between the pollen concentration and onset of symptoms of patients were analyzed.RESULTS Spring pollen showed two peaks,the first peak from March 25 to April 9;another peak from April 24 to May 24.Onset of symptoms in pure group was correlated with the pollen concentration in spring.Symptoms of nasal and eye itching in pure group were severer than that in combined group（P〈0.01）;and symptom score of nasal obstruction in combined group were higher than pure group（P〈0.01）.CONCLUSION Pollen concentration may have a major effect on onset of symptoms of allergic rhinitis.Airborne pollen monitoring has important preventive and therapeutic significance on the patients with allergic rhinitis.

关 键 词：花粉 鼻炎 变应性 季节性 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]