多变根毛霉致面部皮肤毛霉病1例  

A case of primary cutaneous mucormycosis caused by Rhizomucor variabilis

作　　者：周村建[1] 王莉[1] 徐艳[1] 钟白玉[1] 郝飞[1] 

机构地区：[1]第三军医大学西南医院皮肤性病科,重庆400038

出　　处：《中国真菌学杂志》2011年第6期361-362,共2页Chinese Journal of Mycology

摘　　要：报道1例由多变根毛霉引起的面部皮肤毛霉病。患者男,65岁,面部结节斑块伴痒半年余。皮损组织病理检查示真皮中下层有炎细胞及多核巨细胞浸润,并见粗大较短的无隔菌丝。经真菌培养和分子生物学鉴定,菌种鉴定为多变根毛霉。皮损经短时两性霉素B治疗后好转。A 65-year-old man with diffused swelling plaques in the face for half a year was reported.Characteristic broad,non-septate hyphae were found in the lesion by histopathology.The isolate was identified as Rhizomucor variabilis by fungal culture,PCR and sequence analysis.The patient was diagnosied as primary cutaneous mucormycosis and improved after systemic amphotericin B for 12 days,with total dosage of 1 050 mg.

关 键 词：皮肤毛霉病 多变根毛霉 两性霉素B 

分 类 号：R756.6[医药卫生—皮肤病学与性病学]