全脊柱终板抗压强度分布规律的生物力学研究  

Biomechanical study of compressive strength distribution on the whole spine endplates

作　　者：李光灿[1] 李康华[2] 郑连杰[1] 李靖年[1] 李正维[1] 刘晓凯 李志刚[4] 

机构地区：[1]大连医科大学附属第二医院骨科,大连116023 [2]中南大学湘雅医院骨科,长沙410008 [3]朝阳市中心医院骨科,朝阳122000 [4]大连大学附属中山医院骨科,大连116001

出　　处：《医用生物力学》2011年第6期521-526,554,共7页Journal of Medical Biomechanics

摘　　要：目的通过测量全脊柱不同椎体上下终板不同位点的抗压强度,研究全脊柱终板抗压强度的分布规律。方法选用5具成年男性新鲜脊柱标本(C3～S1),共225个终板。对终板平面49个测试点用平底压头进行压缩加载试验,获得最大破坏载荷。结果 (1)全脊柱终板抗压强度呈颈腰椎较强、胸椎较弱趋势(P<0.01)。抗压强度自C3～7逐渐减小,在T1水平增大,然后再次逐渐减小,至T7降至最低,自T8开始增强,至L4达到强度最大值,L5复又降低后,S1再次增大。(2)除C5和T1外,下终板抗压强度大于上终板(P<0.01)。(3)除C5/6,T12/L1和L5/S1间隙外,椎间隙相邻面上一椎体下终板的抗压强度大于下一椎体上终板。(4)中央至外周抗压强度逐渐增大(P<0.05)。(5)处于不同角度组的压力点,其抗压强度存在差异(P<0.01)。(6)全脊柱终板不同节段前后强度分布不同(P<0.01)。C3/4后侧终板强度大于前部,C5～7前后部大体持平,至T1再次后部大于前部,经过T2～5过渡段后,自T6～L3出现前部抗压强度大于后部,L4再次相对均衡,至L5、S1出现后部抗压强度大于前部。结论全脊柱不同节段终板和终板不同部位的强度分布与脊柱生理弯曲关系密切。抗压强度下终板高于上终板,外周大于中央,椎间隙相邻面上一椎体下终板大于下一椎体上终板。Objective To study distributions of the compressive strength on the whole spine endplates by measuring the compressive strength at different locations of the whole spine endplates. Methods Indentation tests were performed at 49 locations in 225 bony endplates of intact human vertebrae （C3-S]） from ,5 fresh male specimens to record the failure loads. Results （]） For the whole spine endplates, failure loads of the cervical and lumbar spine were found to be higher than those of the thoracic spine （ P 〈 0.0] ）. The failure load was first decreased from C3 to C7 before increasing to T], and then dropping through -I-7 and rising again from T8, reacNng the maxi- mum at L4, and dropping at 1_5 before increasing again at S]. （2） The failure load at inferior cervical endplates was significantly higher than that at superior endplates except at C5 and T! （ P 〈 0.05）. （3） Within the interverte- bral space, the cranial endplates had a higher yield stress than the caudal endplates except at C5/6, T]2/L] and U/S]. （4） Failure loads were generally increased from the central to peripheral zones （P 〈 0.05）. （5） For dif-ferent angular points, failure load distributions were found among the endplates （ P 〈 0, 01 ~. （6） Distributions of the compressive strength on the endplates varied significantly within the whole spine（ P 〈 0.01 ）. It was found that at C3/4, the failure load at posterior was higher than that at anterior, but at C5/6, the failure load at posterior and anterior was balanced. At TI, the failure load was found to be higher at posterior again, until passing through T2- 5, and at T6-1_3, the failure load at anterior was higher than that at posterior, and balanced between the anterior and posterior again at L4. At I_＇^-Sl, the failure load at posterior was higher than that at anterior. Conclusions The strength distributions on the endplates varied significantly at different locations within the whole spine, which was closely correlated with the physiological curve o

关 键 词：脊柱 终板 抗压强度 破坏荷载 力学测试 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程]