我院住院患者2008-2010年抗菌药物使用强度分析  

Analysis of Antibacterial Use Density in the Inpatients of Our Hospital from 2008 to 2010

作　　者：史桂玲[1] 张惠娟[1] 孙秀颖[1] 周存霞[1] 蒋媛[1] 

机构地区：[1]天津市人民医院药剂科,天津300121

出　　处：《中国药房》2012年第6期510-512,共3页China Pharmacy

摘　　要：目的:了解我院住院患者抗菌药物的应用情况及趋势。方法:采用回顾性方法,对我院2008-2010年住院患者的抗菌药物使用强度(AUD)进行统计、分析。结果:我院住院患者抗菌药物的AUD3年来呈明显的下降趋势,由2008年的64.25DDD/100人/天下降到2010年的57.96DDD/100人/天。第3代头孢菌素、氟喹诺酮类和第2代头孢菌素为AUD最大的前3类抗菌药物,AUD最大的科室依次为ICU、妇产科、VIP科、呼吸内科、儿科。结论:从总体来看,我院抗菌药物的AUD低于全国平均水平,但仍存在某些科室滥用抗菌药物、医师偏爱价格昂贵的广谱抗菌药物等问题。应严格限制第3、4代头孢菌素、氟喹诺酮类药的临床应用,提高合理用药水平。OBJECTIVE： To investigate the application and trend of antibacterials in the inpatients of our hospital. METHODS ： By retrospective study, antibacterial use density （AUD） in the inpatients of our hospital was analyzed statistically from 2008 to 2010. RESULTS： The AUD of the inpatients in our hospital was in decreasing tendency in the past 3 years, decreasing from 64.255 DDD/100 persons/d in 2008 to 57.96 DDD/100 persons/d in 2010. The most frequently used antibacterials were third-generation cepha- losporins, fluoroquinolones and second-generation cephalosporins. The highest AUD in different departments or sections in sequence were ICU, gynaecology and obstetrics department, VIP department, respiratory department and pediatrics department. CONCLUSIONS： On the whole, AUD of our hospital is lower than national average level. But there are still some departments which have the abuse of antibacterials, and expensive broad-spectrum antibacterials are still some doctors＇ preferences. Third/fourth-generation cepha- losporins and fluoroquinolones should be strictly restricted in clinical application, in order to improve rational use of drugs.

关 键 词：抗菌药物 限定日剂量 使用强度 用药分析 

分 类 号：R969.3[医药卫生—药理学] R287[医药卫生—药学]