脂筏标记蛋白flotillin-2生理功能的研究进展  

Advances in study on physiological functions of marker protein of lipid raft flotillin-2

作　　者：赵峰[1] 张杰[1] 李丽 

机构地区：[1]中国农业科学院兰州兽医研究所家畜疫病病原生物学国家重点实验室,甘肃兰州730046 [2]成都市金堂县淮口镇人民政府,四川成都610404

出　　处：《中国兽医科学》2012年第1期107-110,共4页Chinese Veterinary Science

基　　金：国家自然科学基金资助项目(30671563;31072143)

摘　　要：为了给进一步研究flotillin-2与某些神经退行性疾病(如海绵状脑病等)的关系提供参考,对脂筏标记蛋白flotillin-2的结构及其主要的生理功能进行了综述,提出,进一步研究flotillin-2与某些神经组织退化疾病及肿瘤的关系,对疯牛疯、克雅病、阿尔兹罕默氏病以及肿瘤病的发病机制及治疗研究具有重要意义。This article reviews the structure and major physiological functions of flotillin-2 confirmed as a marker protein of lipid raft in order to provide references for studying the relationship between flotillin-2 and some neurodegenerative diseases（i, e. spongiform encephalopathy,etc. ）. It was pointed out that it was important for further studying of the relationship of flotillin-2 with neurodegenerative diseases and tumor,which was of great important studying on pathogenesis and treatment approaches of bovine spongiform encephalopathy,Creutzfeld-Jakob disease, Alzheimer ＇ s disease and tumor.

关 键 词：flotillin-2 脂筏 朊蛋白 

分 类 号：S852.23[农业科学—基础兽医学]