气导短纯音诱发的眼肌前庭诱发肌源性电位在健康青年人群中的波形特征  

Characteristics of the air-conducted ocular evoked myogenic potential in the young normal Chinesesubjects

作　　者：张青 宋辉[1] 胡娟 陈彦飞 张滟 杜小滢[1] 张全安 韦俊荣[1] 许珉 加我君孝 

机构地区：[1]西安交通大学医学院第二附属医院耳鼻咽喉头颈外科病院,西安交通大学医学院耳病研究所 [2]日本东京医疗中心日本国立感觉器官研究所

出　　处：《中华耳鼻咽喉头颈外科杂志》2012年第1期15-18,共4页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：科技部“十一五”科技支撑计划项目（2007BAll8813）;国家自然科学基金（3073300/c170703）;西安交通大学医学院第二附属医院2011年新技术新疗法基金（2011015）;西安交通大学校长基金（xjj2008019）

摘　　要：目的 介绍气导短纯音诱发的眼肌前庭诱发肌源性电位（ocular vestibular evoked myogenic potential,oVEMP）的引出方法；观察健康青年人群oVEMP反应,并进行参数分析和正常值计算.方法 选择25名健康成人作为研究对象,其中男12名,女13名,年龄19～ 45岁,平均年龄（24.3±5.6）岁.以500 Hz短纯音为刺激音,进行气导oVEMP检测,并计算阈值、潜伏期等参数的正常值.结果 全部受试者均引出典型的oVEMP N1-P1复合波形,引出率为100％.oVEMP的引出阈值（正常听力级）为（86.6 ±3.6）dB（（x）±s,下同）；N1潜伏期为（10.1 ±0.4） ms,P1潜伏期为（14.7±1.2）ms,波间期（4.5±1.0）ms；振幅（7.9±4.4） μV.除振幅耳间波动稍大外,oVEMP阈值、N1潜伏期及P1潜伏期左右耳间波动很小.结论 气导oVEMP是一种新兴的、稳定有效的前庭功能检测方法.Objective To identify the characteristics of the air-conducted ocular vestibular-evoked myogenic potential（oVEMP） in the young normal Chinese subjects.Methods Twenty five normal subjects were recruited for conventional examinations of oVEMP.The subjects were 19 - 45 years of age [ （24.3 ± 5.6） years ],12 males and 13 females.500 Hz air-conducted tone burst was employed for examination.The threshold of oVEMP in each ear was examined; patterns of these waves were observed and the normal ranges of the oVEMP waves responded to 100 dBnHL were calculated.Results All subjects were elicited with normal oVEMP N1-P1 waves in both ears.The response rate in these subjects was 100%.The threshold of oVEMP examination was （ 86.6 ± 3.6） dBnHL （ （x） ± s）,latency N1 （ 10.1 ± 0.4 ） ms,latency P1 （ 14.7 ±1.2） ms,interval N1-P1 （ 4.5 ± 1.0 ） ms,amplitude （ 7.9 ± 4.4 ） μV.Conclusions Air-conducted oVEMP is a kind of vestibular-ocular reflex respond to intensive sound generated by otolithic vestibular end organs.It is stable in the young normal subjects with minor variabilities.

关 键 词：球囊和椭圆囊 前庭功能试验 

分 类 号：R764[医药卫生—耳鼻咽喉科]