超临界萃取技术在中药有效成分提取中的应用  

Application of supercritical fluid extraction technology in extraction of effective components in Chinese materia medica

作　　者：张在娟[1] 任晓文[2] 王博[2] 严苏梅 连潇嫣[2] 

机构地区：[1]天津中医药大学中药学院,天津300193 [2]天津药物研究院制剂技术及研究中心,天津300193 [3]太钢总医院药剂科,山西太原030003

出　　处：《现代药物与临床》2011年第6期444-447,共4页Drugs & Clinic

基　　金：天津市科技支撑项目(09ZCKFSH01200)

摘　　要：近年来超临界流体萃取(supercritical fluid extraction,SFE)技术凭借萃取速度快、流程短、效率高、能耗少、可在较低温度下操作以及可以与GC、IR等分析手段联用等优越性已经成为萃取中药有效成分的重要技术手段。综述了SFE技术在中药有效成分如挥发性、萜类、生物碱、黄酮类及其苷、酚类、不饱和脂肪酸和香豆素类成分提取中的应用,并对该技术的发展趋势进行了展望。In recent years, supercritical fluid extraction （SFE） technology has become an essential method in extraction of active ingredients for extraction of Chinese materia medica depending on fast extraction, short process, high efficiency, energy consumption, operating at lower temperature and being combined with GC and IR analysis methods. This article summarizes its applications in the separation and extraction of active ingredients, such as volatile components, effective components of terpene, alkaloid, active ingredients flavonoids, phenolic active ingredients, unsaturated fatty acids, active ingredient coumarin and so on. Finally, the development trends of the technology are prospected.

关 键 词：超临界流体萃取 中药 有效成分 提取 超临界流体 

分 类 号：R282.4[医药卫生—中药学]