某院神经外科围术期抗菌药物应用分析  

Perioperative Use of Antibiotics in Neurosurgical Patients in a Hospital

作　　者：丁志杰[1] 张洪峰[1] 刘芬[1] 张项红[1] 王乐[1] 

机构地区：[1]邯郸市中心医院药剂科,邯郸056001

出　　处：《中国医院用药评价与分析》2011年第12期1092-1095,共4页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:调查某院神经外科围术期抗菌药物用药现状,并进行客观分析,指导临床合理用药。方法:回顾性调查某院神经外科2010年4月—2010年11月出院的神经外科手术病历164例,记录相关信息,进行统计分析。结果:164例病例中全部使用了抗菌药物,涉及抗菌药物8大类30个品种,使用频率较高的是第2代头孢菌素、β-内酰胺及β-内酰胺酶抑制剂和第3代头孢菌素。结论:某院神经外科围术期抗菌药物的使用不尽合理,手术预防用药档次高、时限超规定、用药时机不当;治疗性用药做细菌培养和药敏试验率低;频繁换药缺乏病原学检查,无指征联合用药等。OBJECTIVE： To probe into the status quo of the perioperative use of antibacterial drugs in neurosurgical patients in a hospital with an objective analysis for references of clinical rational drug use.METHODS： By a retrospective study,a total of 164 medical histories of neurosurgical patients discharged between Apr.2010 and Jan.2010 were reviewed with the relevant information recorded for a statistical analysis.RESULTS： All of the 164 patients received antibiotics.The antibiotics totaled 8 categories and 30 varieties.The most frequently used antibiotics were the second generation cephalosporins,β-lactamase inhibitors and the third generation cephalosporins.CONCLUSION： The perioperative utilization of antibiotics in the neurosurgical patients in this hospital was irrational to some extent such as high drug level in preventive medication,the time limit going beyond specification,inappropriate timing of administration,low rate for bacterial culture and drug sensitivity test before drug use,frequent change of drugs in the absence of etiology test and drug combination in the absence of indications etc.

关 键 词：围术期 抗菌药物 调查分析 

分 类 号：R978.1[医药卫生—药品]