HIV/AIDS病人中接受和未接受抗病毒治疗人群生存质量的调查分析  

A survey of the quality of life of people living with HIV/AIDS receiving and not receiving highly active antiretroviral treatment

作　　者：闫存玲[1] 吴群红[1] 王福祥[2] 郝艳华[1] 李文静[2] 张锋镝[2] 李航[2] 

机构地区：[1]哈尔滨医科大学卫生管理学院,哈尔滨150081 [2]哈尔滨医科大学第一临床医学院感染科,哈尔滨150001

出　　处：《中国艾滋病性病》2011年第6期629-632,共4页Chinese Journal of Aids & STD

基　　金：美国中华医学基金会健康中国2020项目(08-929)~~

摘　　要：目的对艾滋病病毒(HIV)感染者和艾滋病(AIDS)病人中,接受和未接受高效抗反转录病毒治疗(HAART)人群的生存质量进行描述和比较,探讨生存质量的影响因素。方法横断面调查研究,采用人口学问卷、WHOQOL-HIV-BRIEF中文简表、Berger耻辱量表收集信息,运用SPSS 13.0统计软件进行数据的分析。结果收回有效问卷155份。HIV/AIDS病人的生存质量除精神支柱/个人信仰维度外,均低于全国常模,差异均有统计学意义(P<0.01);治疗组生存质量除总体生存状况和健康状况外,均低于未治疗组,并且在独立性维度差异有统计学意义(t=-2.725,P<0.01);治疗组HIV耻辱量表得分明显低于未治疗组(t=2.208,P<0.05)。多因素分析提示,年龄、受教育程度、婚姻状况、收入水平、是否因艾滋病住过院以及HIV耻辱总分,均与生存质量有关(P<0.05),其中HIV耻辱得分与生存质量呈负相关。结论加强抗病毒治疗人群的症状管理,倡导减少艾滋病相关歧视,建立理解、宽容的生存环境。Objective To describe and compare the quality of life of people living with HIV/AIDS（PLWHA） receiving and not receiving highly active antiretroviral treatment（HAART）and explore the impact factors.Methods A cross-sectional survey which applied demographic,WHOQOL-HIV-BRIEF,HIV-related stigma was conducted to collect information and the collected data were analyzed with SPSS 13.0.Result One hundred and fifty five valid questionnaires were returned.The overall quality of life of PLWHA was lower than that of the general population except for mental support and spiritual belief,and the difference had statistical significance（P0.01）.The quality of life of PLWHA receiving HAART（HAART group） was lower than that of those not receiving HAART（non-HAART group） except for general survival conditions and health status,and there was a significant difference in independence（t=-2.725,P0.01）;HIV-related stigma（t=2.208,P0.05） in HAART group was significantly lower than that in non –HARRT group.Multivariate analysis indicated that age,education,marriage,income,hospitalization and HIV-related stigma were all associated with quality of life（P0.05）.Among these factors,HIV-related stigma presented a negative correlation with quality of life.Conclusion Symptom management should be strengthened among PLWHA receiving HAART,and reduction of HIV-related stigma should be advocated and an environment of understanding and tolerance should be established.

关 键 词：艾滋病病毒感染者/艾滋病病人 高效抗反转录病毒治疗 生存质量 耻辱 

分 类 号：R512.91[医药卫生—内科学]