男男性行为人群队列保持的影响因素研究  

Factors associated with cohort retention among men who have sex with men

作　　者：柳昭羽[1,2] 吴国辉[3] 徐杰[2] 丁贤彬[3] 米国栋[2] 欧阳琳[3] 斗智[2] 柔克明[2] 吴尊友[2] 

机构地区：[1]北京协和医学院公共卫生学院,中国医学科学院,北京100730 [2]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [3]重庆市疾病预防控制中心,重庆400042

出　　处：《中国艾滋病性病》2011年第6期646-650,共5页Chinese Journal of Aids & STD

基　　金：“十一五”“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项(2008ZX10001-016);中国多学科艾滋病结核防治培训(项目编号5U2RTW 006918)~~

摘　　要：目的探讨男男性行为人群(MSM)艾滋病病毒(HIV)血清学阳转的前瞻性队列保持影响因素。方法 2009年3-10月,在重庆市采用分类滚雪球的方法,招募HIV抗体检测阴性的MSM,2010年3月和9月分别进行两次随访调查,随访联系以移动电话和网络聊天工具通知为主,并在随访联系中逐一调查研究对象的失访情况。分析研究对象的社会人口学和行为学特征,以及对队列保持的影响。结果基线进入队列的453名MSM,有299人至少参加了一次随访,随访率为66.0%。单因素和多因素分析显示,年龄>25岁、本市居住时间>1年、近1年做过艾滋病检测与近6个月发生无保护男男肛交性行为和较高的保持率密切相关(P<0.05)。结论低年龄段、本地居住时间较短、近1年未做过艾滋病检测、近6个月未发生无保护男男肛交性行为的MSM,相比之下更不易保持在队列中,需要在MSM队列研究时引起注意。Objective To investigate factors associated with the retention of men who have sex with men（MSM） in an HIV prospective cohort study.Method From March to October of 2009,HIV negative MSM were recruited into a prospective cohort study by using classified snowball sampling.The first follow-up period began in March of 2010 and the second in September of 2010.Mobile phone and Internet based communication tools were used as the main contacting methods.Meanwhile,detailed information about MSM who were lost to follow-up was recorded during the contact.The socio-demographic characteristics and behavior which might affect the retention were analyzed.Result A total of 453 MSM were successfully recruited at the baseline,of whom 299 were followed up at least once,and the follow up rate was 66.0%.In both single factor and multiple logistic regression analysis,the factors including age over 25 years,living locally for more than 1 year,receiving HIV test in the past one year,having unprotected anal intercourse with men during the past six months,were found to be associated with high retention rate（P0.05）.Conclusion It is harder to retain MSM in the cohort study who are younger,living locally for less than one year,receiving no HIV test in the past one year,and having unprotected anal intercourse with men in the past 6 months,and all these factors should be given serious attention during the MSM cohort study.

关 键 词：男男性行为人群 艾滋病 队列研究 随访 影响因素 

分 类 号：R373.9[医药卫生—病原生物学]