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机构地区:[1]武汉市妇女儿童医疗保健中心心脏外科,武汉市430016
出 处:《临床小儿外科杂志》2011年第6期417-419,共3页Journal of Clinical Pediatric Surgery
摘 要:目的总结2002年1月至2011年4月作者收治的15例先天性心脏病合并感染性心内膜炎(infective endocarditis,IE)患儿手术治疗中的体外循环经验(cardiopulmonary bypass,CPB)。方法15例患儿均采用浅低温(28℃~30℃)、较高流量[2.4~3.2L/(min·m2)]灌注。手术方式为畸形矫治(ASD/VSD修补、右室流出道重建)、赘生物摘除、瓣膜整形或置换术。心肌保护采用4℃冷含血晶体保护液顺行灌注。结果15例患儿CPB总时间85~180min,主动脉阻断时间40~120min,均顺利脱离CPB。均获痊愈。1例术后2年死于肺部感染及心功能衰竭。结论CPB中HCT及胶体渗透压的良好控制、采用平衡超滤结合改良超滤、肝素化后监测ACT、CPB中加入敏感抗生素等对患儿术后恢复至关重要。Objective To summarize retrospectively the clinical experience of cardiopulmonary bypass (CPB) in pediatric congenital heart disease (CHD) complicated by infective endoearditis (IE) from January 2002 to April 2011 (15 eases). Methods CPB was performed with Shallow low temperature(28℃ -30℃ ) and high flow rate [ 2.4 - 3.2L/( min · m2 ) ] perfusion. Operation method for Correcting the heart abnormality (ASD/VSD repaired, Right ventricular outflow reconstructed ), excrescence excision, valve plastic or replacemerit. 4 ℃ cold crystalloid with blood was perfused by antegrade perfusion for myocardial protection. Results Among the total time CPB 85 - 180 min, aortic blocking time 40 - 120 min, 15 cases of patients were smoothly disconnected from CPB. All cases recovered completely. 1 case died in lyear due to heart failure. Conclusion The important factors in CPB are the good adjustment in colloid osmotic pressure(COP) and hematocrit ( HCT), Balance uhrafihration ( BUF ) and modified uhrafiltration ( MUF), monitor of activated clotting time (ACT) ,sensitive antibiotics used in priming liquid.
分 类 号:R542.42[医药卫生—心血管疾病]
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