Pretreatment of Isopropanol Solution from Pharmaceutical Industry and Pervaporation Dehydration by NaA Zeolite Membranes  

作　　者：余从立 刘艳梅 陈纲领 顾学红 邢卫红 

机构地区：[1]State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, Nanjlng210009, China

出　　处：《Chinese Journal of Chemical Engineering》2011年第6期904-910,共7页中国化学工程学报（英文版）

基　　金：Supported by the National t）asic Research Program of China （2009CB623403）, the National High Technology Research and De velopment Program of China （2009AA034802）, the National Natural Science Foundation of China （20706030, U0834004）, the Science ＆ Technology Support Program （Industry） of Jiangsu Province of China （BE2008141）, the Natural Science Foundation of the Jiangsu Higher Education Institutions （09KJA530002） and 333 High-Level Personnel Training Project in Jiangsu Province. ＊＊ To whom correspondence should be addressed. E-mail： [e-mail]

摘　　要：NaA zeolite membranes with 80 cm in length and 12.8 mm in outer diameter were prepared by our research group cooperating with Nanjing Jiusi Hi-Tech Co., China. The influence of dissolved inorganic salts and pH value in the feed of isopropanol （IPA） solution on NaA zeolite membranes was investigated. It was found that both factors exhibited strong influence on the stability of NaA zeolite membranes. A set of pretreatment steps such as pH adjustment and distillation of the IPA solution were proposed to improve stability for pervaporation dehydration. An industrial-scale pervaporation facility with 52 m2 membrane area was built to dehydrate IPA solution from industrial cephalosporin production. The facility was continuously operated at 368-378 K to dehydrate IPA solution from water mass content of 15%-20% to less than 2% with a feed flow rate of 400-500 L·h^-1 and an average water flux of 1-1.5 kg·m^-2·h-1. The successful application of this facility suggested a promising application of NaA zeolite mem-brane for IPA recovery from pharmaceutical production.有在长度的 80 厘米和在外部直径的 12.8 公里的 NaA 沸石膜被我们与南京 Jiusi 高技术公司合作的研究组准备，中国。在 isopropanol (国际语音学协会) 的 feed 的溶解的无机的盐和 pH 价值的影响 NaA 沸石膜上的答案被调查。两个因素在 NaA 沸石膜的稳定性上展出了强烈影响，这被发现。象 pH 调整和 IPA 溶液的蒸馏那样的一套预告的处理步被建议为 pervaporation 脱水改进稳定性。有 52 m2 膜区域的一台工业规模的 pervaporation 设备被造从工业头孢霉菌素生产使国际语音学协会答案脱水。设备连续地在 368378 K 被操作从有 400500 的 feed 流动率的到不到 2% 的 15%20% 的内容在 37 慳畴慲楴湯愠摮挠浯数楴楴湯攠灸牥浩湥獴? 湡 ? 畦据楴湯污挠 ? 带了的水质量使国际语音学协会答案脱水 ? 瑳摵敩吗？

关 键 词：NaA zeolite membrane ISOPROPANOL DEHYDRATION PERVAPORATION 

分 类 号：TQ028.8[化学工程] TQ424.25