儿童厌食症危险因素的1:4配比病例对照研究  

A 1:4 matched case-control study on risk factors of anorexia in children

作　　者：刘伶[1] 陆晓梅[1] 徐济达[1] 张娟[1] 王嵘[1] 敖淑清[1] 

机构地区：[1]南京医科大学公共卫生学院卫生检验学系,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2011年第12期1879-1881,共3页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏省教育厅科研基金资助(JH B05-25)

摘　　要：目的:探索儿童厌食症发生的危险因素。方法:以社区为基础的1∶4配比病例对照研究,结合问卷调查和血清维生素A测定,采用条件Logistic回归模型分析危险因素。结果:多因素条件Logistic回归分析显示,儿童进食不定量(OR=1.500,95%CI=1.071～2.101,P=0.018)、挑食偏食(OR=1.780,95%CI=1.267～2.501,P=0.001)、家长强制儿童进食(OR=2.133,95%CI=1.491～3.054,P<0.001)、患有消化道疾病(OR=3.106,95%CI=1.955～4.933,P<0.001)、近2周患有呼吸道感染(OR=1.669,95%CI=1.112～2.513,P=0.013)、出生后喂养困难(OR=1.946,95%CI=1.284～2.950,P=0.002)以及血维生素A缺乏(OR=3.222,95%CI=1.660～6.256,P=0.001)与厌食症存在显著关联。结论:应该纠正儿童不良饮食习惯,普及科学知识以及适时补充维生素A,以减少儿童厌食症的发生。Objective：To explore risk factors for anorexia in children.Methods：A community-based 1：4 matched case-control study was conducted using questionnaire survey and vitamin A detection.Conditional logistic regression was used to estimate odds ratio.Results：Multivariate conditional Logistic regression analysis showed that Feeding without ration（OR=1.500,95%CI=1.071～ 2.101,P = 0.018）,Partiality for a particular kind of food（OR=1.780,95%CI=1.267～2.501,P = 0.001）,Be forced to feed by paterfamilias（OR=2.133,95%CI= 1.491～3.054,P〈 0.001）,Be ill with digestive diseases（OR=3.106,95%CI=1.955～4.933,P 〈0.001）,Be ill with respiratory infection in recent two weeks（OR=1.669,95%CI=1.112～2.513,P = 0.013）,Feeding hardly just after birth（OR= 1.946,95CI=1.284～2.950,P = 0.002） and Be lack of vitamin A（OR=3.222,95%CI=1.660～6.256,P = 0.001） are associated significantly with anorexia in children.Conclusion：Prevention and control measurements should be focused on the bad habits of children,nutritional knowledge of their parents and timely vitamin A rich foods intake to reduce the risk of anorexia.

关 键 词：厌食症 病例对照研究 危险因素 

分 类 号：R723.19[医药卫生—儿科]