胚胎性横纹肌肉瘤误诊1例报告及文献复习  

Misdiagnosis of ovarian embryonal rhabdomyosarcoma:A case report and literature review

作　　者：张海艳[1] 孟元光[1] 李亚里[1] 李立安[1] 范文生[1] 胡凌云[1] 陈乐真[1] 

机构地区：[1]解放军总医院妇产科,北京100853

出　　处：《军医进修学院学报》2012年第1期84-87,共4页Academic Journal of Pla Postgraduate Medical School

基　　金：国家自然科学基金项目(30872749)~~

摘　　要：目的探讨胚胎性横纹肌肉瘤(embryonal rhabdomysarcoma,ERMS)的诊断要点及治疗方案。方法报道我院2011年3月接诊的卵巢胚胎性横纹肌肉瘤患者临床资料,搜集国内外女性生殖系统横纹肌肉瘤误诊报道文献,汇总国内外治疗无瘤存活超过30个月的治疗方案,并进行分析。结果误诊报道共4例,1例死亡后尸检确诊ERMS,其余误诊3例都接受了局部手术及后续治疗,临床效果不满意;无瘤存活超过30个月的文献报道共39例,早期占87.88%,该组接受了以手术为主的积极治疗,预后较好。结论胚胎性横纹肌肉瘤诊断依据临床症状、病理检查和免疫组化,预后差,治疗以手术等综合治疗为主。Objective To study the diagnosis, treatment and prognosis of embryonal rhabdomysarcoma（ERMS）. Methods Clinical data about one ERMS patient admitted to our hospital in March 2011 were reported. Domestic and foreign literature on misdiagnosis of ERMS in female reproductive system was collected and information on the treatment modalities for ERMS patients with a tumor- free survival time for over 30 months was analyzed. Results Of the 4 reported misdiagnosed cases, 1 was finally diagnosed as ERMS by autopsy, the other 3 misdiagnosed cases were treated with local surgery and follow-up treatment with a poor outcome. Thirty-nine cases with a tumor-free survived time for over 30 months were reported and early stage ERMS accounted for 87.88%. The prognosis of these patients was rather good after surgery-based active treatment. Conclusion The incidence of ERMS is low, especially in the female urogenital system. The diagnosis of ERMS mainly depends on its clinical symptoms, pathological and immunohistochemical examination. It is mainly treated with surgery and its prognosis is poor.

关 键 词：胚胎性横纹肌肉瘤 葡萄状肉瘤 女性生殖系统 诊断 治疗 

分 类 号：R711.75[医药卫生—妇产科学]