InCl_3-mediated intramolecular Friedel-Crafts-type cyclization and its application to construct the [6-7-5-6] tetracyclic scaffold of liphagal  

作　　者：JIANG Hao TIAN LuFeng LI ZhenTao LIU Qi LI ChuangChuang YAO XinSheng YANG Zhen 

机构地区：[1]Institute of Traditional Chinese Medicine and Natural Products,Jinan University,Guangzhou 510632,China [2]Laboratory of Chemical Genomics,Shenzhen Graduate School of Peking University,Shenzhen 518055,China and Center for Life Sciences,Beijing 100871,China

出　　处：《Science China Chemistry》2012年第1期36-42,共7页中国科学（化学英文版）

基　　金：supported by the grants of National Basic Research Program(973 Program,2010CB833201 & 2009CB940904);the National Science and Technology Major Project "Development of Key Technology for the Combinatorial Synthesis of Privileged Scaffolds" (2009ZX09501-012);the National Natural Science Foundation of China(20821062,20832003 and 20902007)

摘　　要：A unified strategy toward the construction of the [5.7.6]tricyclic skeleton of liphagal is reported,featuring InCl3-mediated intramolecular Friedel-Crafts-type cyclization.A unified strategy toward the construction of the [5.7.6]tricyclic skeleton of liphagal is reported,featuring InCl3-mediated intramolecular Friedel-Crafts-type cyclization.

关 键 词：synthesis liphagal InCl3-mediated intramolecular Friedel-Crafts ANNULATION 

分 类 号：O561.3[理学—原子与分子物理] S511.03[理学—物理]