麻醉趋势指数预测全麻苏醒期患者意识水平的有效性  

Value of Narcotrend index in prediction of level of consciousness in analepsia patients with general anesthesia

作　　者：王森[1] 闫诺[1] 杨程[1] 李宏[1] 陈宁[1] 

机构地区：[1]武警医学院附属医院麻醉科,天津300162

出　　处：《海南医学院学报》2012年第1期113-115,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020120033)~~

摘　　要：目的:探讨麻醉趋势指数(narcotrend index,NI)预测全麻苏醒期患者意识水平的有效性。方法:30例择期全麻手术患者,ASAⅠ级或Ⅱ级,应用Narcotrend麻醉深度监测仪监测NI。静脉麻醉诱导,靶控输注丙泊酚维持麻醉。记录患者在苏醒期对刺激无反应、呼之睁眼即刻、定向力恢复各时点的NI、丙泊酚的效应室靶浓度(effect site concentration,Ce)、MAP及HR。结果:随着患者意识逐渐恢复,NI逐渐升高,Ce逐渐降低(P<0.01)。NI、MAP、HR均与意识水平呈正相关,Ce与意识水平呈负相关。在呼之睁眼即刻-定向力恢复阶段,NI的预测概率(prediction probability,Pk)值显著高于0.5(P<0.05),Ce、MAP、HR的Pk值与0.5比较,差异无统计学意义(P>0.05)。结论:NI能够有效预测全麻苏醒期患者的意识水平。Objective： To discuss value of Narcotrend index（NI） in prediction of level of consciousness in analepsia patients with general anesthesia.Methods：A total of 30 cases with scheduled general anthelia,ASA ⅠorⅡ level were selected.NI was monitored by Narcotrend monitor.With induction of intravenous anesthesia,anesthesia was maintained by target controlled infusion of propofol.Reaction to stimuli,eye opening as calling,NI at various times of orientation force recovery,target effect-site propofol concentration（Ce）,MAP and HR were recorded.Results：As recovery of consciousness,NI was significantly increased,and Ce was significantly decreased（P0.01）.NI,MAP and HR were positively related with level of consciousness.At the time of eye opening as calling and recovery period of orientation force,prediction probability（Pk） of NI was significantly higher than 0.5（P0.05）.There was no significant difference in Pk between Ce,MAP,HR and 0.5（P0.015）.Conclusions：NI is effective on prediction of level of consciousness in analepsia patients with general anesthesia.

关 键 词：麻醉趋势指数 预测 全麻苏醒期 意识 

分 类 号：R614.2[医药卫生—麻醉学]