茵莲汤治疗糖尿病足及对神经电生理影响的相关性研究  

Treatment of diabetic foot with Yin Lian Tang and its neurophysiological effects

作　　者：吴寅[1] 王璐[2] 邹玲梅[3] 王建生[2] 欧红芹[3] 

机构地区：[1]安徽省蚌埠市第三人民医院中医内科,233000 [2]安徽省蚌埠市第三人民医院中西医结合科,233000 [3]安徽省蚌埠市第三人民医院内分泌科,233000

出　　处：《淮海医药》2012年第1期1-2,共2页Journal of Huaihai Medicine

基　　金：安徽省蚌埠市科技局2008年立项课题(200827)

摘　　要：目的介绍茵莲汤治疗糖尿病足及对神经电生理影响的相关性研究。方法研究纳入Wagner分级1～4级的糖尿病足患者60例,分为对照组和治疗组。治疗组在常规治疗的基础上,采用具有清热利湿解毒功效的茵莲汤进行治疗,并配合外洗方煎水泡足。3个月后评估溃疡愈合情况,并复查空腹血糖、餐后2 h血糖、糖化血红蛋白、血尿常规、肝肾功能、心电图及神经传导速度。结果治疗组总体疗效方面明显优于对照组,同时在降低餐后2 h血糖、总胆固醇、低密度脂蛋白胆固醇,提高胫神经和腓总神经传导速度方面明显优于对照组。结论茵莲汤配合外洗方具有降糖、降脂、加速溃疡愈合,提高神经传导速度的作用,可有效提高糖尿病足患者的生活质量,减少截肢率。Objective To study the treatment of diabetic foot with Yin Lian Tang and its neurophysiological effects. Methods 60 patients with diabetic foot （ Wagner grade 1 to 4 ） were enrolled and divided into 2 groups. Yin Lian Tang was administered, based on the conventional treatment in the treatment group, and the affected food was immersed in decocted Chinese medicine water. After 3 months＂ follow-up, tile healing of ulcer, fasting plasma glucose, 2-hour postprandial blood glucose, glycated hemoglobin, urine routine, blood routine, liver and kidney function, ECG, and nerve conduction velocity were assessed and reviewed. Results The treatment group was better than the control group in overall efficacy, and gained advantage over the control group in lowering 2-hour postprandial blood glucose, total cholesterol, low-density lipoprotein cholesterol, and improving the conduction velocity of tibial nerve and common peroneal nerve. Conclusion Yin Lian Tang combined with washing affected foot can lower blood sugar and lipids, accelerate ulcer healing and improve nerve conduction, which can effectively improve the life quality of patients with diabetic foot and reduce the amputation rate.

关 键 词：糖尿病足 茵莲汤 清热利湿解毒 神经电生理 

分 类 号：R242[医药卫生—中医临床基础]