Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis  

作　　者：ManTong  ZhuoLv  LeiLiu  HuiZhu  Qin-YuanZheng  Xiao-YangZhao  WeiLi  Yi-BoWu  Hai-JiangZhang  Hua-JunWu  Zhi-KunLi  FanyiZeng  LiuWang  Xiu-JieWang  Jia-HaoSha QiZhou 

机构地区：[1]State Key Laboratory of Reproductive Biology,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China [2]State Key Laboratory of Reproductive Medicine,Nanjing Medical University,Nanjing 210029,China [3]Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China [4]Shanghai Institute of Medical Genetics,Shanghai Children's Hospital,Shanghai Jiao Tong University,Shanghai 200040,China [5]Graduate School,TheChinese Academy of Sciences,Beijing 100049,China [6]Institute of Medical Science, Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China

出　　处：《Cell Research》2011年第11期1634-1637,共4页细胞研究(英文版)

摘　　要：Dear Editor, Ever since the creation of induced pluripotent cells (iPSCs) from adult somatic cells by the ectopic expres- sion of defined transcription factors [1, 2], whether iPS cells are equivalent to embryonic stem cells (ESCs) in function and safety aspects has been a major.

关 键 词：胚胎干细胞 iPS 四倍体 相似 小鼠 主管 互补 肿瘤 

分 类 号：Q813[生物学—生物工程] TP393.08[自动化与计算机技术—计算机应用技术]